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Melasma and Its Effect on Quality of Life: A Cross-Sectional Perspective Publisher



Ghale RA1, 2 ; Nasimi M3 ; Alidoost S4 ; Talebi M5 ; Ghale RA1, 2 ; Rahmani M4 ; Pouresmaeili F6, 7
Authors
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Authors Affiliations
  1. 1. Physical Medicine and Rehabilitation Department, Emam Khomeini Hospital, Tehran University of Medical Science, Tehran, Iran
  2. 2. AstraBionics Research Network (ARN), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  3. 3. Autoimmune Bullous Disease Research Center, Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Razi Hospital, Vahdate Eslami Street, Tehran, Iran
  4. 4. Department of Energy and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran
  5. 5. Student Research Committee, Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  6. 6. Medical Genetics Department, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  7. 7. Men’s Health and Reproductive Health Research Center (MHRHRC), Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Dermatology Practical and Conceptual Published:2025


Abstract

Introduction: Melasma is a skin disorder that causes brown spots on the face, especially in females and people with dark skin. This situation can have a significant impact on the patient’s quality of life, including issues with self-confidence, mental strain, and difficulty in social and familial relationships. Objectives: This study aimed to evaluate the quality of life of patients with melasma. Methods: We conducted a study analyzing the relationship between the severity of melasma and quality of life using the Dermatology Life Quality Index (DLQI) questionnaire. Results: The study found that severity of melasma, which was measured by the Melasma Area and Severity Index (MASI), was closely related to the degree of maximum darkness in the affected area. The researchers also found a modest impact on quality of life related to the condition, with DLQI scores averaging 6.16, and a strong correlation between MASI scores and quality of life. Conclusions: Healthcare professionals should also consider the emotional and societal consequences of skin pigmentation conditions in addition to providing medical and therapeutic interventions. Further research is needed to better understand the complex relationships between different factors and their impact on skin health. ©2024 Almasi Ghale et al.