Synthesis of a Carbon-14 Analog of 8-Chloro-11- (4-Methyl-1-Piperazinyl)-11-[14C]-5H-Dibenzo[B,E][1,4]Diazepine (Clozapine) Using Microwave Irradiation

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Synthesis of a Carbon-14 Analog of 8-Chloro-11- (4-Methyl-1-Piperazinyl)-11-[14C]-5H-Dibenzo[B,E][1,4]Diazepine (Clozapine) Using Microwave Irradiation Publisher

Saadatjoo N¹ ; Javaheri M^{1, 2} ; Saemian N² ; Amini M³

Show Affiliations

1. Department of Organic Chemistry, Faculty of Chemistry, Semnan University, P.O. Box 35131-19111, Semnan, Iran
2. Applied Radiation Research School, Nuclear Science and Technology Research Institute, P.O. Box 11365-3486, Semnan, Iran
3. Department of Medicinal Chemistry, Faculty of Pharmacy and Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran, 14176, Iran

Source: Radiochemistry Published:2016

Abstract

8-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine labeled with 14C in 11-position was synthesized in four steps from [carboxyl-14C]anthranilic acid using microwave irradiation with good overall radiochemical yield. © 2016, Pleiades Publishing, Inc.

Style	Citing Format
MLA	Saadatjoo N, et al.. "Synthesis of a Carbon-14 Analog of 8-Chloro-11- (4-Methyl-1-Piperazinyl)-11-[14C]-5H-Dibenzo[B,E][1,4]Diazepine (Clozapine) Using Microwave Irradiation." Radiochemistry, vol. 58, no. 4, 2016, pp. 423-425.
APA	Saadatjoo N, Javaheri M, Saemian N, Amini M (2016). Synthesis of a Carbon-14 Analog of 8-Chloro-11- (4-Methyl-1-Piperazinyl)-11-[14C]-5H-Dibenzo[B,E][1,4]Diazepine (Clozapine) Using Microwave Irradiation. Radiochemistry, 58(4), 423-425.
Chicago	Saadatjoo N, Javaheri M, Saemian N, Amini M. "Synthesis of a Carbon-14 Analog of 8-Chloro-11- (4-Methyl-1-Piperazinyl)-11-[14C]-5H-Dibenzo[B,E][1,4]Diazepine (Clozapine) Using Microwave Irradiation." Radiochemistry 58, no. 4 (2016): 423-425.
Harvard	Saadatjoo N et al. (2016) 'Synthesis of a Carbon-14 Analog of 8-Chloro-11- (4-Methyl-1-Piperazinyl)-11-[14C]-5H-Dibenzo[B,E][1,4]Diazepine (Clozapine) Using Microwave Irradiation', Radiochemistry, 58(4), pp. 423-425.
Vancouver	Saadatjoo N, Javaheri M, Saemian N, Amini M. Synthesis of a Carbon-14 Analog of 8-Chloro-11- (4-Methyl-1-Piperazinyl)-11-[14C]-5H-Dibenzo[B,E][1,4]Diazepine (Clozapine) Using Microwave Irradiation. Radiochemistry. 2016;58(4):423-425.
BibTex	@article{ author = {Saadatjoo N and Javaheri M and Saemian N and Amini M}, title = {Synthesis of a Carbon-14 Analog of 8-Chloro-11- (4-Methyl-1-Piperazinyl)-11-[14C]-5H-Dibenzo[B,E][1,4]Diazepine (Clozapine) Using Microwave Irradiation}, journal = {Radiochemistry}, volume = {58}, number = {4}, pages = {423-425}, year = {2016} }
RIS	TY - JOUR AU - Saadatjoo N AU - Javaheri M AU - Saemian N AU - Amini M TI - Synthesis of a Carbon-14 Analog of 8-Chloro-11- (4-Methyl-1-Piperazinyl)-11-[14C]-5H-Dibenzo[B,E][1,4]Diazepine (Clozapine) Using Microwave Irradiation JO - Radiochemistry VL - 58 IS - 4 SP - 423 EP - 425 PY - 2016 ER -

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