Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! By
Dentin Remineralizing Potential of a Bioactive Composite Resin Versus a Conventional Composite Resin: Mineral Index and Microhardness Analysis Publisher



F Motevaselian FARIBA ; B Mohaghegh BEHNAM ; F Sadeghi Mahounak FARZANEH ; N Rafeie NIYOUSHA ; M Abbasi MAHDI ; Lr Omran Ladan RANJBAR
Authors

Source: Journal of Research in Dental and Maxillofacial Sciences Published:2025


Abstract

Background and Aim: This study aimed to compare the dentin demineralization inhibitory potential of a bioactive composite resin (ACTIVA-BioActive) with a conventional composite resin. Materials and Methods: In this in vitro experimental study, 45 class V cavities were prepared on the root surface of extracted human third molars. The teeth were then immersed in a demineralizing solution (lactic acid, pH=4.5) at 37˚C for 3 days to induce the formation of secondary caries. The cavities were restored with Single bond 2 + Z250 (group A), ACTIVA BioActive (group B), and Single bond 2 + ACTIVA BioActive (group C). The dentin microhardness was measured close to the restoration margin (marginally exposed dentin), and at approximately 4 mm distance from the margin in a varnish-covered dentin area (protected dentin). Three measurements were made at each site at 50, 100, and 150 µm depths from the external dentin surface. Data were analyzed with one-way ANOVA and Tukey test (alpha=0.05). Results: The highest Vickers hardness number (VHN) was observed in ACTIVA+ bonding agent (49.46±4.15), followed by Z250 (44.57±3.87), and ACTIVA (43.44±3.76) group. The mineral index was significantly higher in ACTIVA+ bonding agent (76.87±3.80) compared to other groups while no significant difference was observed between ACTIVA (70.85±4.06) and Z250 (71.98±3.09) in this regard (P<0.001). Conclusion: The results showed that flowable ACTIVA BioActive composite used with Single bond 2 resulted in a significantly smaller reduction in dentin microhardness and reduced secondary caries formation. ACTIVA BioActive with no adhesive had no advantage over Z250 composite. © 2025 Elsevier B.V., All rights reserved.
Related Docs
View other Related Docs
1. Marginal Microleakage and Modified Microtensile Bond Strength of Activa Bioactive, in Comparison With Conventional Restorative Materials, Clinical and Experimental Dental Research (2022)
2. The Effect of the Bioactive Glass and the Er:Yag Laser on the Remineralization of the Affected Dentin: A Comparative in Vitro Study, Journal of Lasers in Medical Sciences (2020)
3. Effect of Bioinductive Cavity Liners on Shear Bond Strength of Dental Composite to Dentin, BioMed Research International (2022)
Experts (# of related papers)
View all Related Experts
Fariba Motevaselian (2)
Elham Ahmadi (2)
Other Related Docs
4. Comparison of Dentin Caries Remineralization With Four Bioactive Cements, European Journal of Prosthodontics and Restorative Dentistry (2022)
5. Microshear Bond Strength of Different Adhesive Systems to Dentin, Frontiers in Dentistry (2019)
6. Effect of Temperature of 1.23% Acidulated Phosphate Fluoride Gel on Enamel Microhardness of Permanent Teeth, International Journal of Dentistry (2024)
7. Fracture Strength and Three-Dimensional Marginal Evaluation of Biocompatible High-Performance Polymer Versus Pressed Lithium Disilicate Crowns, Journal of Prosthetic Dentistry (2023)
8. Evaluation of the Effects of 810 Nm Diode Laser Alone and in Combination With Gluma© and Chromophore on Dentinal Tubule Occlusion: A Scanning Electron Microscopic Analysis, Journal of Lasers in Medical Sciences (2020)
9. Comparison of the Effect of Qmix and Conventional Root Canal Irrigants on Push-Out Bond Strength of Fiber Post to Root Dentin, Clinical and Experimental Dental Research (2022)
10. Effect of Photodynamic Therapy With Two Photosensitizers on the Microtensile Bond Strength of a Universal Adhesive to Affected Dentin, Photodiagnosis and Photodynamic Therapy (2024)
11. Shear Bond Strength of Molar Tubes to Enamel Using an Orthodontic Resin-Modified Glass Ionomer Cement Modified With Amorphous Calcium Phosphate, Frontiers in Dentistry (2019)
12. Fracture Resistance of Three Different Posts in Restoration of Severely Damaged Primary Anterior Teeth: An in Vitro Study, Dental Research Journal (2015)
13. Comparison of Microleakage of an Alkasite Restorative Material, a Composite Resin and a Resin-Modified Glass Ionomer, Brazilian Journal of Oral Sciences (2021)
14. An in Vitro Comparison of the Bond Strength of Composite to Superficial and Deep Dentin, Treated With Er:Yag Laser Irradiation or Acid-Etching, Journal of Lasers in Medical Sciences (2016)
15. The Effect of Laser-Activated Bleaching With 810 Nm and 980 Nm Diode Lasers on Enamel Micro-Hardness; an in Vitro Study, Laser Physics (2020)
16. Effect of Modified 45S5 Bioglass on Physical and Chemical Properties of Bleached Enamel, Brazilian Journal of Oral Sciences (2019)
17. Evaluation of the Effects of Different Types of Resin Cement Systems on the Push-Out Bond Strength of the Fiber Post to Intracanal Dentin in Anterior Primary Teeth, International Journal of Dentistry (2023)
18. Effect of Antimicrobial Photodynamic Therapy With Different Photosensitizers and Adhesion Protocol on the Bond Strength of Resin Composite to Sound Dentin, Clinical Oral Investigations (2022)
19. Comparative Analysis of Adhesive Retention and Denture Weight in Different Residual Ridge Morphologies: A Cross-Over Randomized-Controlled Trial, Clinical and Experimental Dental Research (2025)
20. Tissue Engineering: Dentin – Pulp Complex Regeneration Approaches (A Review), Tissue and Cell (2017)