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Dentin Remineralizing Potential of a Bioactive Composite Resin Versus a Conventional Composite Resin: Mineral Index and Microhardness Analysis Publisher



F Motevaselian FARIBA ; B Mohaghegh BEHNAM ; F Sadeghi Mahounak FARZANEH ; N Rafeie NIYOUSHA ; M Abbasi MAHDI ; Lr Omran Ladan RANJBAR
Authors

Source: Journal of Research in Dental and Maxillofacial Sciences Published:2025


Abstract

Background and Aim: This study aimed to compare the dentin demineralization inhibitory potential of a bioactive composite resin (ACTIVA-BioActive) with a conventional composite resin. Materials and Methods: In this in vitro experimental study, 45 class V cavities were prepared on the root surface of extracted human third molars. The teeth were then immersed in a demineralizing solution (lactic acid, pH=4.5) at 37˚C for 3 days to induce the formation of secondary caries. The cavities were restored with Single bond 2 + Z250 (group A), ACTIVA BioActive (group B), and Single bond 2 + ACTIVA BioActive (group C). The dentin microhardness was measured close to the restoration margin (marginally exposed dentin), and at approximately 4 mm distance from the margin in a varnish-covered dentin area (protected dentin). Three measurements were made at each site at 50, 100, and 150 µm depths from the external dentin surface. Data were analyzed with one-way ANOVA and Tukey test (alpha=0.05). Results: The highest Vickers hardness number (VHN) was observed in ACTIVA+ bonding agent (49.46±4.15), followed by Z250 (44.57±3.87), and ACTIVA (43.44±3.76) group. The mineral index was significantly higher in ACTIVA+ bonding agent (76.87±3.80) compared to other groups while no significant difference was observed between ACTIVA (70.85±4.06) and Z250 (71.98±3.09) in this regard (P<0.001). Conclusion: The results showed that flowable ACTIVA BioActive composite used with Single bond 2 resulted in a significantly smaller reduction in dentin microhardness and reduced secondary caries formation. ACTIVA BioActive with no adhesive had no advantage over Z250 composite. © 2025 Elsevier B.V., All rights reserved.
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