Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Noncommunicable Disease Syndemic Among the General Population in Iran: A Cross-Sectional Study Publisher



Torabi Z1 ; Farzadfar F2 ; Rezaei N2 ; Singer M3 ; Roshani S4 ; Tajvar M5 ; Shakibazadeh E1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Health Education and Promotion, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Noncommunicable Diseases Research Centre, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Anthropology, University of Connecticut, 354 Mansfield Road, Storrs, 06269, CT, United States
  4. 4. The Netherlands Cancer Institute (NKI), Amsterdam, Netherlands
  5. 5. Department of Health Management, Policy and Economic, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Diabetes and Metabolic Disorders Published:2025


Abstract

Objectives: This study aims to investigate the status of the NCD syndemic among individuals over 25 in all provinces of Iran. Methods: This study was based on a national survey. Using a systematic cluster random sampling framework, 26,707 participants were selected from all 31 Iranian provinces. The data were analyzed for descriptive statistics by gender and age, followed by principal component analysis and logistic regression, using R software for the statistical analysis. Results: There was an interaction between diabetes mellitus and cardiovascular diseases, in their association with healthy life lost due to disability in the Iranian adult population. Additionally, there was a clustering of diabetes mellitus and cardiovascular diseases, partly due to the shared specific causes such as obesity, hypertension, shared baseline features, and poverty. Conclusions: The syndemic analysis showed that social inequalities in diabetes and cardiovascular disease arise not only from exposure levels but also from varying vulnerabilities and disease outcomes. Iran’s health policy should prioritize reducing these health inequalities. © The Author(s), under exclusive licence to Tehran University of Medical Sciences 2025.
Related Docs
1. The Clinical Value of Metabolic Syndrome and Its Components With Respect to Sudden Cardiac Death Using Different Definitions: Two Decades of Follow-Up From the Tehran Lipid and Glucose Study, Cardiovascular Diabetology (2022)
2. Utilization Patterns of Cardiovascular Medications in Patients With Diabetes Mellitus; a Retrospective Cross-Sectional Study, 2013-17, DARU# Journal of Pharmaceutical Sciences (2023)
3. Antihypertensive Drug Effects on Long-Term Blood Pressure: An Individual-Level Data Meta-Analysis of Randomised Clinical Trials, Heart (2022)
4. Adult Weight Gain and the Risk of Cardiovascular Disease: A Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies, European Journal of Clinical Nutrition (2020)
5. Sex-Dependent Effects of Diabetes Mellitus on the Revascularization Rate in Mid-Term Follow up of Young Patients With Coronary Artery Disease, Journal of Diabetes and its Complications (2017)
6. Prevalence, Awareness, Treatment, and Control of Hypertension Based on Acc/Aha Versus Jnc7 Guidelines in the Persian Cohort Study, Scientific Reports (2022)
7. Impact of 2017 Acc/Aha Guideline on Prevalence, Awareness, Treatment, Control, and Determinants of Hypertension: A Population-Based Cross-Sectional Study in Southwest of Iran, Population Health Metrics (2021)
8. The Global Syndemic of Obesity, Undernutrition, and Climate Change: The Lancet Commission Report, The Lancet (2019)
Experts (# of related papers)
View all Related Experts
Sadaf Ghajarieh Sepanlou (2)
Hossein Poustchi (2)