Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Mid-Term Outcome Following Pipeline Embolization of Unruptured Intracranial Aneurysms Publisher



Firouznia K1 ; Hosseiny M1 ; Kooraki S1 ; Samani A1 ; Soltani M1 ; Jalali AH1 ; Parhizgar SE1 ; Ghanaati H1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Advanced Diagnostic and Interventional Radiology Research Center(ADIR), Medical imaging Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Radiology Published:2018


Abstract

Background: As an advanced generation of flow diverters (FD), pipeline embolization device (PED) is introduced for endovascular aneurysm occlusion. In the present study, we aimed to present the mid-term results after endovascular treatment of unruptured intracranial aneurysms using PED. Patients and Methods: A total of 20 patients with 20 intracranial wide neck aneurysms were treated with PED between July and October 2010. Patients were followed up 4 to 8 months after the procedure. Digital subtraction angiography (DSA) was carried out to assess stent integrity, displacement, and the presence of residual aneurysm. Results: Out of 20 participants, PED deployment was successful in 19; whereas, intervention failed in one patient due to technical factors in device deployment. No severe acute complications were observed. One patient died after three months as a result of subarachnoid hemorrhage (SAH). Out of the remaining patients, DSA showed complete occlusion of aneurysms in 14 individuals (77.8%), while in four patients (22.2%), residual aneurysm was noted. Stent migration was not observed in any patients. Intra-stent stenosis (25% - 50%) was visualized in only one patient (5.5%). Conclusion: This study showed promising mid-term results for the pipeline embolization device in the treatment of unruptured intracranial aneurysms. Larger studies with longer follow-up duration are warranted. © 2017, Iranian Journal of Radiology.