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Persistent Lip Enlargement: An Unusual Presentation of Lupus Erythematosus Publisher



Nikoo A1 ; Daneshpazhooh M2 ; Fahim S2 ; Ghanadan A1 ; Mahmoudi H2 ; Izadi Firoozabadi L2
Authors
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Authors Affiliations
  1. 1. Department of Dermatopathology, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Autoimmune Bullous Diseases Research Center, Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran

Source: International Journal of Women's Dermatology Published:2017


Abstract

Macrocheilia is a challenging problem with a variety of underlying causes that are both local and systemic, and granulomatous causes underlie the majority of cases. In this study, we report on a 31-year old man who presented with a chronic lower lip enlargement and a nodular submental erythematous lesion. He was otherwise clinically healthy. Laboratory test results were within the normal limit except for a positive anti-double stranded DNA test result. A diagnosis of cutaneous lupus erythematosus was made on the basis of histopathology and direct immunofluorescence. The lesions resolved dramatically after treatment with hydroxychloroquine. Lupus erythematosus should be considered when examining patients who present with chronic lip swelling. © 2016 The Author(s)