Physicochemical- and Biocompatibility of Oxygen and Nitrogen Plasma Treatment Using a Pla Scaffold

Physicochemical- and Biocompatibility of Oxygen and Nitrogen Plasma Treatment Using a Pla Scaffold Publisher

Davoodi A¹ ; Zadeh HH² ; Joupari MD³ ; Sahebalzamani MA⁴ ; Khani MR⁵ ; Shahabi S⁶

Show Affiliations

1. Dental Biomaterials Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
2. VISTA Institute for Therapeutic Innovations, 6325 Topanga Canyon Blvd., Woodland Hills, 91367, CA, United States
3. Department of Animal Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran
4. Department of Biomaterials, Faculty of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran
5. Laser and Plasma Research Institute, Shahid Beheshti University, G.C., Evin, Tehran, 1983963113, Iran
6. Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran

Source: AIP Advances Published:2020

Abstract

Plasma surface treatment has a wide range of applications in biomedicine. In the present study, flat polylactic acid (PLA) films were treated with oxygen and nitrogen, low-pressure, non-thermal plasma. The water contact angle of the PLA films dramatically decreased from 67° in the untreated surface to 34° and 38° in surfaces treated with nitrogen and oxygen plasma, respectively. Conversely, after the plasma treatment, the surface free energy of the films increased considerably from 45.73 mN/m to 66.51 mN/m. The hydrophilicity potential variations following the plasma treatment were measured by the x-ray photoelectron spectroscopy examination of polar functional groups. Furthermore, surface changes after plasma treatment were examined using atomic force microscopy. The MTT assay showed no changes in cell viability cytotoxicity following the PLA films' plasma treatment. Moreover, as evidenced by SEM analysis, plasma treatment was found to promote cell growth and adhesion to polymer surfaces. The results were suggestive of modifications due to the PLA's plasma treatment that may enhance the biological properties of PLA as a scaffold. © 2020 Author(s).

Style	Citing Format
MLA	Davoodi A, et al.. "Physicochemical- and Biocompatibility of Oxygen and Nitrogen Plasma Treatment Using a Pla Scaffold." AIP Advances, vol. 10, no. 12, 2020, pp. -.
APA	Davoodi A, Zadeh HH, Joupari MD, Sahebalzamani MA, Khani MR, Shahabi S (2020). Physicochemical- and Biocompatibility of Oxygen and Nitrogen Plasma Treatment Using a Pla Scaffold. AIP Advances, 10(12), -.
Chicago	Davoodi A, Zadeh HH, Joupari MD, Sahebalzamani MA, Khani MR, Shahabi S. "Physicochemical- and Biocompatibility of Oxygen and Nitrogen Plasma Treatment Using a Pla Scaffold." AIP Advances 10, no. 12 (2020): -.
Harvard	Davoodi A et al. (2020) 'Physicochemical- and Biocompatibility of Oxygen and Nitrogen Plasma Treatment Using a Pla Scaffold', AIP Advances, 10(12), pp. -.
Vancouver	Davoodi A, Zadeh HH, Joupari MD, Sahebalzamani MA, Khani MR, Shahabi S. Physicochemical- and Biocompatibility of Oxygen and Nitrogen Plasma Treatment Using a Pla Scaffold. AIP Advances. 2020;10(12):-.
BibTex	@article{ author = {Davoodi A and Zadeh HH and Joupari MD and Sahebalzamani MA and Khani MR and Shahabi S}, title = {Physicochemical- and Biocompatibility of Oxygen and Nitrogen Plasma Treatment Using a Pla Scaffold}, journal = {AIP Advances}, volume = {10}, number = {12}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Davoodi A AU - Zadeh HH AU - Joupari MD AU - Sahebalzamani MA AU - Khani MR AU - Shahabi S TI - Physicochemical- and Biocompatibility of Oxygen and Nitrogen Plasma Treatment Using a Pla Scaffold JO - AIP Advances VL - 10 IS - 12 SP - EP - PY - 2020 ER -

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