Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Priase 2021 Guidelines for Reporting Animal Studies in Endodontology: A Consensus-Based Development Publisher Pubmed



Nagendrababu V1 ; Kishen A2 ; Murray PE3 ; Nekoofar MH4 ; De Figueiredo JAP5 ; Priya E6 ; Jayaraman J7 ; Pulikkotil SJ8 ; Camilleri J9 ; Silva RM10 ; Dummer PMH11
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Preventive and Restorative Dentistry, College of Dental Medicine, University of Sharjah, Sharjah, United Arab Emirates
  2. 2. Faculty of Dentistry, University of Toronto, Toronto, ON, Canada
  3. 3. Private Consultant, Fort Lauderdale, FL, United States
  4. 4. Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Federal University, Porto Alegre, Brazil
  6. 6. Division of Children and Community Oral Health, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia
  7. 7. Department of Developmental Dentistry, University of Texas Health School of Dentistry, San Antonio, TX, United States
  8. 8. Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia
  9. 9. School of Dentistry, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom
  10. 10. Department of Endodontics, School of Dentistry, University of Texas Health Science Center at Houston, Houston, TX, United States
  11. 11. School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff, United Kingdom

Source: International Endodontic Journal Published:2021


Abstract

Animal testing is crucial in situations when research on humans is not allowed because of unknown health risks and ethical concerns. The current project aims to develop reporting guidelines exclusively for animal studies in Endodontology, using an established consensus-based methodology. The guidelines have been named: Preferred Reporting Items for Animal Studies in Endodontology (PRIASE) 2021. Nine individuals (PD, VN, AK, PM, MN, JF, EP, JJ and SJ), including the project leaders (PD, VN) formed a steering committee. The steering committee developed a novel checklist by adapting and integrating their animal testing and peer review experience with the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guidelines and also the Clinical and Laboratory Images in Publications (CLIP) principles. A PRIASE Delphi Group (PDG) and PRIASE Online Meeting Group (POMG) were also formed. Thirty-one PDG members participated in the online Delphi process and achieved consensus on the checklist items and flowchart that were used to formulate the PRIASE guidelines. The novel PRIASE 2021 guidelines were discussed with the POMG on 9 September 2020 via a Zoom online video call attended by 21 individuals from across the globe and seven steering committee members. Following the discussions, the guidelines were modified and then piloted by several authors whilst writing a manuscript involving research on animals. The PRIASE 2021 guidelines are a checklist consisting of 11 domains and 43 individual items together with a flowchart. The PRIASE 2021 guidelines are focused on improving the methodological principles, reproducibility and quality of animal studies in order to enhance their reliability as well as repeatability to estimate the effects of endodontic treatments and usefulness for guiding future clinical studies on humans. © 2021 International Endodontic Journal. Published by John Wiley & Sons Ltd
Related Docs
1. Priase 2021 Guidelines for Reporting Animal Studies in Endodontology: Explanation and Elaboration, International Endodontic Journal (2021)
2. Preferred Reporting Items for Animal Studies in Endodontology: A Development Protocol, International Endodontic Journal (2019)
3. Preferred Reporting Items for Study Designs in Endodontology (Pride): Guiding Authors to Identify and Correct Reporting Deficiencies in Their Manuscripts Prior to Peer Review, International Endodontic Journal (2020)
Experts (# of related papers)
Mohammad Hossein Nekoofar (3)