Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Effect of Probiotics in Prevention of Necrotising Enterocolitis in Preterm Neonates in Comparison With Control Group Publisher



Amini E1 ; Dalili H2 ; Niknafs N1 ; Shariat M1 ; Nakhostin M2 ; Jedariattari S1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Maternal-Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Breastfeeding Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Pediatrics Published:2017


Abstract

Background: Necrotizing enterocolitis (NEC) is a common dangerous gastrointestinal emergency in neonatology, especially in premature infants, which can cause serious problems. Objectives: This study was conducted to find out whether administration of probiotics could lead to prevention and/or treatment of NEC. Methods: 115 premature newborns weighting 750-1500 g or less than 32 weeks’ gestation were checked daily for NEC signs and weight gain and mean day of full feed achievement was recorded. Results: The incidence of NEC and C-reactive protein (CRP) rise showed a significant difference (P = 0.02) between the two (case and control) groups, but the difference regarding mean duration of oxygen therapy, TPN, full feeding achievement, and hospitalization was not significant. Conclusions: These results showed positive effects of probiotics on preventing and treating NEC, especially NEC grade 3 in ELBW and VLBW neonates. © 2017, Iranian Journal of Pediatrics.
Related Docs
1. Safety of Probiotic Bacteria, Probiotics# Prebiotics# and Synbiotics: Bioactive Foods in Health Promotion (2016)
Experts (# of related papers)