Isolation of Lactobacillus Acidophilus and Assessment for Its Antiviral Effect Against Herpes Simplex Virus Type Ii

Isolation of Lactobacillus Acidophilus and Assessment for Its Antiviral Effect Against Herpes Simplex Virus Type Ii Publisher

Goudarzi MM¹ ; Fazeli MR²

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1. Department of Microbiology, Islamic Azad University, Science and Research Branch, Tehran, Iran
2. Department of Drug and Food Control, Pharmaceutical Quality Assurance Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Molecular Genetics# Microbiology and Virology Published:2015

Abstract

The prevalence of diverse genital infections among women and their increasing resistance to antibiotics has motivated researchers to study the use of probiotics to prevent and treat them. Samples of vaginal discharge were collected from healthy married women. The types of lactobacilli present were identified by biochemical and molecular testing. The antiviral properties of a culture supernatant of wild species or strains of Lactobacillus acidophilus LA-5 on the standard strain of herpes simplex virus type 2 (HSV-2) was evaluated. L. acidophilus culture supernatant significantly decreased the amount of plaque produced by HSV-2 on cells. Similar results were obtained for the standard strain. The inhibitory effect of the wild L. acidophilus did not require the production of H2O2 or H+ ions of the standard strain or an acidic environment. L. acidophilus was able to control HSV-2 without producing H2O2 or H+ ions or acidifying the environment. The inhibitory property of virus is most likely related to production of active metabolites. © 2015, Allerton Press, Inc.

Style	Citing Format
MLA	Goudarzi MM, Fazeli MR. "Isolation of Lactobacillus Acidophilus and Assessment for Its Antiviral Effect Against Herpes Simplex Virus Type Ii." Molecular Genetics# Microbiology and Virology, vol. 30, no. 4, 2015, pp. 237-241.
APA	Goudarzi MM, Fazeli MR (2015). Isolation of Lactobacillus Acidophilus and Assessment for Its Antiviral Effect Against Herpes Simplex Virus Type Ii. Molecular Genetics# Microbiology and Virology, 30(4), 237-241.
Chicago	Goudarzi MM, Fazeli MR. "Isolation of Lactobacillus Acidophilus and Assessment for Its Antiviral Effect Against Herpes Simplex Virus Type Ii." Molecular Genetics# Microbiology and Virology 30, no. 4 (2015): 237-241.
Harvard	Goudarzi MM, Fazeli MR (2015) 'Isolation of Lactobacillus Acidophilus and Assessment for Its Antiviral Effect Against Herpes Simplex Virus Type Ii', Molecular Genetics# Microbiology and Virology, 30(4), pp. 237-241.
Vancouver	Goudarzi MM, Fazeli MR. Isolation of Lactobacillus Acidophilus and Assessment for Its Antiviral Effect Against Herpes Simplex Virus Type Ii. Molecular Genetics# Microbiology and Virology. 2015;30(4):237-241.
BibTex	@article{ author = {Goudarzi MM and Fazeli MR}, title = {Isolation of Lactobacillus Acidophilus and Assessment for Its Antiviral Effect Against Herpes Simplex Virus Type Ii}, journal = {Molecular Genetics# Microbiology and Virology}, volume = {30}, number = {4}, pages = {237-241}, year = {2015} }
RIS	TY - JOUR AU - Goudarzi MM AU - Fazeli MR TI - Isolation of Lactobacillus Acidophilus and Assessment for Its Antiviral Effect Against Herpes Simplex Virus Type Ii JO - Molecular Genetics# Microbiology and Virology VL - 30 IS - 4 SP - 237 EP - 241 PY - 2015 ER -

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Abstract