Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Nsaids and Covid-19: A New Challenging Area Publisher



Baradaran H1 ; Hamishehkar H1 ; Rezaee H1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Clinical Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Source: Pharmaceutical Sciences Published:2020


Abstract

Considering the recent controversies regarding the use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in Coronavirus disease 2019 (COVID-19) patients, and due to the limited published data in this field, we reviewed currently available evidence for the use of NSAIDs in viral respiratory tract infections to help make decisions in this area. Currently, there is insufficient evidence to judge the safety and efficacy of NSAIDs in patients with COVID-19. According to the current evidence, acetaminophen is the choice treatment for symptomatic relief. If the patients' symptoms are not controlled by acetaminophen, naproxen may be used as an alternative therapy. © 2020 The Author(s). This is an open access article and applies the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, as long as the original authors and source are cited.
Related Docs
View other Related Docs
1. Non-Steroidal Anti-Inflammatory Drugs in Management of Covid-19; a Systematic Review on Current Evidence, International Journal of Clinical Practice (2020)
2. Critical Complications of Covid-19: A Descriptive Meta-Analysis Study, Reviews in Cardiovascular Medicine (2020)
3. Cardiovascular Diseases Burden in Covid-19: Systematic Review and Meta-Analysis, American Journal of Emergency Medicine (2021)
4. Clinical Characteristics and Outcomes of 905 Covid-19 Patients Admitted to Imam Khomeini Hospital Complex in the Capital City of Tehran, Iran, Archives of Iranian Medicine (2020)
5. Sars-Cov-2: Current Trends in Emerging Variants, Pathogenesis, Immune Responses, Potential Therapeutic, and Vaccine Development Strategies, International Immunopharmacology (2021)
6. Determine the Most Common Clinical Symptoms in Covid-19 Patients: A Systematic Review and Meta-Analysis, Journal of Preventive Medicine and Hygiene (2020)
7. Covid-19: A Systematic Review and Update on Prevention, Diagnosis, and Treatment, MedComm (2022)
8. Clinical Course and Outcome in Diabetic Patients With Covid-19, Immunopathologia Persa (2021)
Experts (# of related papers)
View all Related Experts
Nima Rezaei (5)
Seyed Ahmad Seyed Alinaghi (4)
Other Related Docs
9. Clinical Symptoms and Types of Samples Are Critical Factors for the Molecular Diagnosis of Symptomatic Covid-19 Patients: A Systematic Literature Review, International Journal of Microbiology (2021)
10. Covid-19 and Multiorgan Failure: A Narrative Review on Potential Mechanisms, Journal of Molecular Histology (2020)
11. Factors Associated With the Poor Outcomes in Diabetic Patients With Covid-19, Journal of Diabetes and Metabolic Disorders (2020)
12. Factors Associated With Covid-19 Morbidity and Mortality: A Narrative Review, Journal of Iranian Medical Council (2020)
13. Pathophysiology of Covid-19 Infection: What Is the Novel Coronavirus (Sars-Cov-2) Doing to Body? a Comprehensive Systematic Review, Reviews and Research in Medical Microbiology (2021)
14. Gastrointestinal Symptoms in Patients With Mild and Severe Covid-19: A Scoping Review and Meta-Analysis, Gastroenterology and Hepatology from Bed to Bench (2020)
15. Repurposing Naproxen As a Potential Nucleocapsid Antagonist of Beta-Coronaviruses: Targeting a Conserved Protein in the Search for a Broad-Spectrum Treatment Option, Journal of Biomolecular Structure and Dynamics (2024)
16. Clinical Characteristics of Fatal Cases of Covid-19 in Tabriz, Iran: An Analysis of 111 Patients, Frontiers in Emergency Medicine (2021)
17. The Clinical Value of Two Combination Regimens in the Management of Patients Suffering From Covid-19 Pneumonia: A Single Centered, Retrospective, Observational Study, DARU# Journal of Pharmaceutical Sciences (2020)
18. Geriatric Challenges in the New Coronavirus Disease-19 (Covid-19) Pandemic: A Systematic Review, Medical Journal of the Islamic Republic of Iran (2020)
19. The Importance of Genomic Changes of Sars-Cov-2 and Its Comparison With Iranian-Reported Covid-19 Sequencing; Whether Each Country Has to Design Its Treatment and Vaccine Production, Biomedical and Biotechnology Research Journal (2020)
20. Possible Transmission Flow of Sars-Cov-2 Based on Ace2 Features, Molecules (2020)
21. Covid-19 Infection and Liver Injury: Clinical Features, Biomarkers, Potential Mechanisms, Treatment, and Management Challenges, World Journal of Clinical Cases (2021)
22. The Primary Outcomes and Epidemiological and Clinical Features of Coronavirus Disease 2019 (Covid-19) in Iran, Advances in Experimental Medicine and Biology (2021)
23. Case Fatality Rate of Covid-19: A Systematic Review and Meta-Analysis, Journal of Preventive Medicine and Hygiene (2021)
24. The Contributory Role of Lymphocyte Subsets, Pathophysiology of Lymphopenia and Its Implication As Prognostic and Therapeutic Opportunity in Covid-19, International Immunopharmacology (2021)
25. Liver Injury Is Associated With Severe Coronavirus Disease 2019 (Covid-19) Infection: A Systematic Review and Meta-Analysis of Retrospective Studies, Hepatology Research (2020)
26. Sars-Cov-2 and Covid-19, Evidence From a Literature Review: Review Article, Tehran University Medical Journal (2021)
27. Cardiovascular Manifestations in Covid-19 Patients: A Systematic Review and Meta-Analysis, Journal of Cardiovascular and Thoracic Research (2021)
28. The Chimera of S1 and N Proteins of Sars-Cov-2: Can It Be a Potential Vaccine Candidate for Covid-19?, Expert Review of Vaccines (2022)
29. A Comprehensive Review on Covid-19 Infection and Comorbidities of Various Organs, Acta Medica Iranica (2021)
30. Well-Controlled Vs Poorly-Controlled Diabetes in Patients With Covid-19: Are There Any Differences in Outcomes and Imaging Findings?, Diabetes Research and Clinical Practice (2020)
31. Acute Cardiac Injury in Covid-19: A Systematic Review and Meta-Analysis, Archives of Iranian Medicine (2020)
32. A Comparative Analysis of Clinical Characteristics and Laboratory Findings of Covid-19 Between Intensive Care Unit and Non-Intensive Care Unit Pediatric Patients: A Multicenter, Retrospective, Observational Study From Iranian Network for Research in Viral Diseases (Inrvd), Frontiers in Emergency Medicine (2021)
33. Assessment of Anorexia and Weight Loss During the Infection and Recovery Period of Patients With Coronavirus Disease 2019 (Covid-19), Clinical Nutrition Open Science (2021)
34. Identifying Data Elements and Key Features of a Mobile-Based Self-Care Application for Patients With Covid-19 in Iran, Health Informatics Journal (2021)
35. Predictors of Hospital Mortality Among Patients With Covid-19 in Tehran, Iran, SAGE Open Medicine (2021)
36. Methylene Blue May Have a Role in the Treatment of Covid-19, Medical Hypotheses (2020)
37. Scientometric Analyzing the Output of Researchers and Organizations on Covid-19 for Better Conducting the Scientific Efforts: With a Glance to Endocrinology, Journal of Diabetes and Metabolic Disorders (2021)
38. Analyzing Trends in Demographic, Laboratory, Imaging, and Clinical Outcomes of Icu-Hospitalized Covid-19 Patients, Canadian Journal of Infectious Diseases and Medical Microbiology (2023)
39. Computed Tomography Scan in Covid-19: A Systematic Review and Meta-Analysis, Polish Journal of Radiology (2022)
40. The Risk Factors and Clinical Outcomes Associated With Acute Kidney Injury in Patients With Covid-19: Data From a Large Cohort in Iran, Kidney and Blood Pressure Research (2021)
41. Are Patients With Multiple Sclerosis (Ms) at Higher Risk of Covid-19 Infection?, Neurological Sciences (2020)
42. Different Incidences of Acute Kidney Injury (Aki) and Outcomes in Covid-19 Patients With and Without Non-Azithromycin Antibiotics: A Retrospective Study, Journal of Medical Virology (2021)
43. Cardiovascular Complications of Covid-19: Pharmacotherapy Perspective, Cardiovascular Drugs and Therapy (2021)
44. Effect of the Chronic Medication Use on Outcome Measures of Hospitalized Covid-19 Patients: Evidence From Big Data, Frontiers in Public Health (2023)
45. Clinical Characteristics and Outcome of Hospitalized Covid-19 Patients With Diabetes: A Single-Center, Retrospective Study in Iran, Diabetes Research and Clinical Practice (2020)
46. A Systematic Review and Meta-Analysis of Pregnancy and Covid-19: Signs and Symptoms, Laboratory Tests, and Perinatal Outcomes, International Journal of Reproductive BioMedicine (2020)
47. Cardiac Complications in Covid-19: A Systematic Review and Meta-Analysis, Archives of Iranian Medicine (2021)
48. Risk and Predictors of In-Hospital Mortality From Covid-19 in Patients With Diabetes and Cardiovascular Disease, Diabetology and Metabolic Syndrome (2020)
49. Clinical Manifestation, Laboratory and Radiology Finding, Treatment and Outcomes of Covid-19: A Systematic Review and Meta-Analysis, Journal of Research in Medical Sciences (2021)
50. Clinical and Radiologic Characteristics of Covid-19 in Patients With Ckd, Iranian Journal of Kidney Diseases (2020)