Molecular Identification of Streptococcus Agalaetiae Using Gbsl805 Gene and Determination of the Antibiotic Susceptibility Pattern of Isolates

Molecular Identification of Streptococcus Agalaetiae Using Gbsl805 Gene and Determination of the Antibiotic Susceptibility Pattern of Isolates

Dehbashi S¹ ; Pourmand MR² ; Mahmoudi M³ ; Mashhadi R⁴

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1. Department of Pathobiology, Sehool of Publie Health, Tehran University of Medieal Seienees, Tehran, IR, Iran
2. Bioteehnology Researeh Center, Tehran University of Medieal Seienees, Tehran, IR, Iran
3. Department of Epidemiology and Biostatisties, Sehool of Publie Health, Tehran University of Medieal Seienees, Tehran, IR, Iran
4. Urology Researeh Centre, Sina Hospital, Tehran University of Medieal Seienees, Tehran, IR, Iran

Source: Journal of Babol University of Medical Sciences Published:2015

Abstract

BACKGROUND AND OBJECTIVE: Streptoeoeeus agalaetiae is the major faetor for sepsis and meningitis in newborns and pneumonia and baeteremia in the elderly. Despite the importanee of this pathogen, no aeeurate statisties are available regarding the prevalenee of assoeiated infeetions in adults. The purpose of this study was to analyse the effieaey of gbs1805 gene in the identifieation of isolates using laboratory and bioinformatie analyses and determine the prevalenee of infeetions eausedby Streptoeoeeus agalaetiae. METHODS: In this eross-seetional study, 522 urine samples and genital swabs were eolleeted from patients with suspeeted urinary traet infeetions and analyzed using eulture and bioehemieal tests. The Streptoeoeeus agalaetiae isolates were examined for the presenee of gbs1805 gene and antibiotie suseeptibility was determined using Clinieal and Laboratory Standards Institute (CLSI) guidelines. FINDINGS: In this study, 54 isolates of Streptoeoeeus agalaetiae (10.3%) were obtained from the infeetions. All the isolates had preserved gbs1805 genes. The highest and lowest sensitivities were related to eeftriaxone (76%) and erythromyein antibioties (33%). CONCLUSION: Identifieation of preserved gbs1805 gene in elinieal samples ean determine infeetions eaused by Streptoeoeeus agalaetiae. Due to the growing resistanee of isolates to penieillin, alternative antibioties should be used for the treatment of infeetions eaused by these baeteria. © 2015, Journal of Babol University of Medical Sciences. All right reserved.

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Mohammad Reza Pourmand (2)

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Style	Citing Format
MLA	Dehbashi S, et al.. "Molecular Identification of Streptococcus Agalaetiae Using Gbsl805 Gene and Determination of the Antibiotic Susceptibility Pattern of Isolates." Journal of Babol University of Medical Sciences, vol. 17, no. 2, 2015, pp. 1-7.
APA	Dehbashi S, Pourmand MR, Mahmoudi M, Mashhadi R (2015). Molecular Identification of Streptococcus Agalaetiae Using Gbsl805 Gene and Determination of the Antibiotic Susceptibility Pattern of Isolates. Journal of Babol University of Medical Sciences, 17(2), 1-7.
Chicago	Dehbashi S, Pourmand MR, Mahmoudi M, Mashhadi R. "Molecular Identification of Streptococcus Agalaetiae Using Gbsl805 Gene and Determination of the Antibiotic Susceptibility Pattern of Isolates." Journal of Babol University of Medical Sciences 17, no. 2 (2015): 1-7.
Harvard	Dehbashi S et al. (2015) 'Molecular Identification of Streptococcus Agalaetiae Using Gbsl805 Gene and Determination of the Antibiotic Susceptibility Pattern of Isolates', Journal of Babol University of Medical Sciences, 17(2), pp. 1-7.
Vancouver	Dehbashi S, Pourmand MR, Mahmoudi M, Mashhadi R. Molecular Identification of Streptococcus Agalaetiae Using Gbsl805 Gene and Determination of the Antibiotic Susceptibility Pattern of Isolates. Journal of Babol University of Medical Sciences. 2015;17(2):1-7.
BibTex	@article{ author = {Dehbashi S and Pourmand MR and Mahmoudi M and Mashhadi R}, title = {Molecular Identification of Streptococcus Agalaetiae Using Gbsl805 Gene and Determination of the Antibiotic Susceptibility Pattern of Isolates}, journal = {Journal of Babol University of Medical Sciences}, volume = {17}, number = {2}, pages = {1-7}, year = {2015} }
RIS	TY - JOUR AU - Dehbashi S AU - Pourmand MR AU - Mahmoudi M AU - Mashhadi R TI - Molecular Identification of Streptococcus Agalaetiae Using Gbsl805 Gene and Determination of the Antibiotic Susceptibility Pattern of Isolates JO - Journal of Babol University of Medical Sciences VL - 17 IS - 2 SP - 1 EP - 7 PY - 2015 ER -

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