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Comparative Efficacy of Hospital Disinfectants Against Nosocomial Infection Pathogens Publisher Pubmed



Amini Tapouk F1 ; Nabizadeh R2, 3 ; Mirzaei N4 ; Hosseini Jazani N5 ; Yousefi M6 ; Valizade Hasanloei MA7
Authors
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Authors Affiliations
  1. 1. Department of Environmental Health Engineering, School of Public Health, International Campus, Tehran University of Medical Sciences (IC-TUMS), Tehran, Iran
  2. 2. Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Center for Air Pollution Research (CAPR), Institute for Environmental Research (IER), Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Environmental Health Engineering, Faculty of Health, Kashan University of Medical Sciences, Kashan, Iran
  5. 5. Department of Microbiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
  6. 6. Department of Environmental Health Engineering, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
  7. 7. Clinical Research Development Unit of Emam Khomeini Hospital, Urima University of Medical Sciences, Urmia, Iran

Source: Antimicrobial Resistance and Infection Control Published:2020


Abstract

Background: Due to the increasing rate of hospital-acquired infections, it is essential to select appropriate disinfectant agents. In this study, the efficacy of hospital disinfectants against nosocomial infection pathogens was compared. Methods: High level disinfectants (Steranios 2%, Deconex HLDPA, and Microzed Quatenol) were tested for their antibacterial effects by determining their minimum inhibitory (MIC) and minimum bactericidal concentrations (MBC) against Enterococcus faecalis ATCC 29212 and Burkholderia cepacia ATCC 10673. Results: E. faecalis, as gram-positive bacterium, was more susceptible to high level disinfectants compared to gram-negative B.cepacia. The MIC = MBC values of 2% Steranios, Deconex HLDPA and Microzed Quatenol against E. faecalis and B.cepacia were 0.31, 9.77, 2.2 mg/L and 9.8, 78.13, 70.31 mg/L, respectively. Conclusions: According to the findings of this study, the most effective disinfectants against both E. faecalis and B.cepacia were Steranios 2%, Microzed Quatenol, and Deconex HLDPA in order. Considering the importance of these bacterial strains in healthcare-associated infections, the use of these effective disinfectants is recommended in the hospitals. © 2020 The Author(s).