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Copper Supported Modified Magnetic Carrageenan As a Bio-Based Catalyst for the Synthesis of Novel Scaffolds Bearing the 1,2,3-Triazole Unit Through the Click Reaction Publisher



Khaleghi N1 ; Esmkhani M2 ; Noori M2 ; Dastyafteh N2 ; Ghomi MK1 ; Mahdavi M1 ; Sayahi MH3 ; Javanshir S2
Authors
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Authors Affiliations
  1. 1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Pharmaceutical and Heterocyclic Compounds Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran
  3. 3. Department of Chemistry, Payame Noor University, Tehran, Iran

Source: Nanoscale Advances Published:2024


Abstract

The ongoing work delineates the design of a novel library of 1,2,3-triazole-attached phenylacetamides through molecular hybridization of propargyl and phenylacetamide derivatives. Copper-supported modified magnetic carrageenan serves as a green heterogeneous catalyst, ensuring high yield, efficient reaction times, high atom economy, utilization of an environmentally friendly catalyst from a natural source, and a straightforward workup procedure. The successful synthesis of the catalyst is confirmed and evaluated using various analytical techniques, while the synthetic compounds are characterized through 1H NMR and 13C NMR. © 2024 RSC.