Investigation of Corona Discharge Ionization of Barbituric Acid Using Ion Mobility Spectrometry Along With Quantum Chemical Calculations

Investigation of Corona Discharge Ionization of Barbituric Acid Using Ion Mobility Spectrometry Along With Quantum Chemical Calculations Publisher Pubmed

Ghahremani M¹ ; Salehabadi H² ; Bahrami H¹ ; Amanlou M^{3, 4}

Show Affiliations

1. Department of Chemistry, University of Zanjan, Zanjan, Iran
2. Department of Medicinal Chemistry, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran
3. Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4. Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran

Source: European Journal of Mass Spectrometry Published:2021

Abstract

This study aimed at examining atmospheric-pressure chemical ionization of barbituric acid through the corona discharge ion mobility spectrometry (CD-IMS) and the quantum chemical calculations. The results indicated two product ion peaks in the IMS spectrum of barbituric acid. The thermal decomposition of the barbituric acid sample was investigated by scanning the temperature of the injection port and analyzing the temporal evolution of the IMS peaks over elapsed time. It was found that the barbituric acid sample was not thermally decomposed in the injection port of the instrument. Experimental evidences were collected by changing the reactant ions, concentration of barbituric acid sample, and IMS cell temperature. The two observed peaks were then assigned to cationic form and oxygen protonated isomers of barbituric acid. The positions of the product ion peaks were explicated considering the dipole moments of the product ions. © The Author(s) 2021.

Style	Citing Format
MLA	Ghahremani M, et al.. "Investigation of Corona Discharge Ionization of Barbituric Acid Using Ion Mobility Spectrometry Along With Quantum Chemical Calculations." European Journal of Mass Spectrometry, vol. 27, no. 1, 2021, pp. 39-47.
APA	Ghahremani M, Salehabadi H, Bahrami H, Amanlou M (2021). Investigation of Corona Discharge Ionization of Barbituric Acid Using Ion Mobility Spectrometry Along With Quantum Chemical Calculations. European Journal of Mass Spectrometry, 27(1), 39-47.
Chicago	Ghahremani M, Salehabadi H, Bahrami H, Amanlou M. "Investigation of Corona Discharge Ionization of Barbituric Acid Using Ion Mobility Spectrometry Along With Quantum Chemical Calculations." European Journal of Mass Spectrometry 27, no. 1 (2021): 39-47.
Harvard	Ghahremani M et al. (2021) 'Investigation of Corona Discharge Ionization of Barbituric Acid Using Ion Mobility Spectrometry Along With Quantum Chemical Calculations', European Journal of Mass Spectrometry, 27(1), pp. 39-47.
Vancouver	Ghahremani M, Salehabadi H, Bahrami H, Amanlou M. Investigation of Corona Discharge Ionization of Barbituric Acid Using Ion Mobility Spectrometry Along With Quantum Chemical Calculations. European Journal of Mass Spectrometry. 2021;27(1):39-47.
BibTex	@article{ author = {Ghahremani M and Salehabadi H and Bahrami H and Amanlou M}, title = {Investigation of Corona Discharge Ionization of Barbituric Acid Using Ion Mobility Spectrometry Along With Quantum Chemical Calculations}, journal = {European Journal of Mass Spectrometry}, volume = {27}, number = {1}, pages = {39-47}, year = {2021} }
RIS	TY - JOUR AU - Ghahremani M AU - Salehabadi H AU - Bahrami H AU - Amanlou M TI - Investigation of Corona Discharge Ionization of Barbituric Acid Using Ion Mobility Spectrometry Along With Quantum Chemical Calculations JO - European Journal of Mass Spectrometry VL - 27 IS - 1 SP - 39 EP - 47 PY - 2021 ER -

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