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Is Narrow Band Imaging Accurate to Differentiate Between High-Risk and Low-Risk Vocal Fold Leukoplakia? a Systematic Review and Meta-Analysis Publisher



Sarabi Jamab M1 ; Aghakouchakzadeh A2 ; Keyhan SO3, 4, 5 ; Rafiemanesh H6, 7 ; Mirzaei A8 ; Teimouri Badeleh Dareh M9
Authors
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Authors Affiliations
  1. 1. Student Research Committee, School of Dentistry, Alborz University of Medical Sciences, Karaj, Iran
  2. 2. Department of Oral and Maxillofacial Pathology, School of Dentistry, Alborz University of Medical Science, Karaj, Iran
  3. 3. DDS, OMFS, College of Dentistry, Department of Oral and Maxillofacial Surgery, Gangneung-Wonju National University, Gangneung, South Korea
  4. 4. Maxillofacial Surgery and Implantology and Biomaterial Research Foundation, Tehran, Iran
  5. 5. Co-Investigator, Department of Oral and Maxillofacial Surgery, College of Medicine, Jacksonville, FL, United States
  6. 6. Assistant Professor, Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran
  7. 7. Department of Epidemiology and Biostatistics, School of Public Health, Alborz University of Medical Sciences, Karaj, Iran
  8. 8. DDS, Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  9. 9. DDS, Student Research Committee, School of Dentistry, Alborz University of Medical Sciences, Karaj, Iran

Source: Oral Oncology Reports Published:2024


Abstract

Vocal fold leukoplakia (VFL) is a pre-cancerous lesion that its management is still a therapeutic dilemma due to the need for timely diagnosis of its nature. Narrow band imaging (NBI) seemed to be beneficial to evaluate VFL. The present review aimed to explore the diagnostic accuracy of NBI in differentiating between low-risk and high-risk VFLs. Thirteen studies met the criteria of this systematic review and 11 of them were included in meta-analysis. The pooled sensitivity and specificity of NBI were 78.02 % (95 % CI: 71.64 %–83.31 %) and 93.70 % (95 % CI: 89.23 %–39.39 %), respectively. Ni 2011 had higher diagnostic accuracy among three main NBI classifications. In conclusion, NBI appeared to be an accurate and useful endoscopic method for evaluating VFL lesions. © 2024 The Authors
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