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Pulmonary Cryptosporidiosis in Hiv Infected Patients at Imam Khomeini Complex Hospital in Tehran, Iran: A Case Series Publisher



Rashidifar S1 ; Gharavi MJ2 ; Harzandi N1 ; Momeni Z1 ; Hasan Nezhad M3
Authors
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Authors Affiliations
  1. 1. Department of Microbiology, Karaj Branch, Islamic Azad University, Karaj, Iran
  2. 2. Department of Parasitology, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Parasitology Published:2025


Abstract

Cryptosporidium species are a significant cause of persistent untreatable diarrhea in HIV-positive patients, especially in developing countries; however, extra-intestinal instances are rarely documented. Herein, we present three cases of pulmonary cryptosporidiosis in HIV patients at Imam Khomeini Hospital, Tehran, Iran. Despite the combination treatment with antiretroviral therapy, azithromycin, and paromomycin, the death of all 3 patients occurred due to severe complications. These cases highlight the importance of early diagnosis and management of respiratory cryptosporidiosis in HIV patients with low CD4 counts. © 2025 Rashidifar et al.
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