Hemicentral Retinal Vein Occlusion in a Patient With a History of Coronavirus Disease 2019 Infection: A Case Report and Review of The Literature Publisher Pubmed



Riaziesfahani H¹ ; Sadeghi R¹ ; Soleymanzadeh M¹ ; Farrokhpour H¹ ; Bazvand F¹ ; Ebrahimiadib N¹ ; Khalili Pour E¹ ; Mirghorbani M¹ Show Affiliations
Source: Journal of Medical Case Reports Published:2024

Abstract

Background: Considering the various manifestations of coronavirus disease 2019 and its imperative importance in terms of the right clinical approach and early management, we sought to present a hemicentral retinal vein occlusion case, with a history of heterozygosity of methylenetetrahydrofolate reductase (MTHFR) genes and potential for clotting complications as a late manifestation of coronavirus disease 2019, and provide a brief review of reported retinal vein occlusion cases in patients with coronavirus disease 2019. Case presentation: A 35-year-old Iranian patient presented with a visual impairment in the left eye 4 months after recovering from coronavirus disease 2019. He reported a mild blurring of vision in the same eye a few days after admission due to coronavirus disease 2019. The ophthalmic evaluation was compatible with hemicentral retinal vein occlusion. Systemic and laboratory workups were negative except for borderline protein C activity, homocysteine levels, and heterozygosity of MTHFR genes. The patient was scheduled to receive three monthly intravitreal antivascular endothelial growth factor injections. Conclusion: We present a case of inferior hemicentral retinal vein occlusion case with an MTHFR mutation with sequential loss of vision 4 months after coronavirus disease 2019 to make clinicians aware of the possibility of late ocular coronavirus disease 2019 manifestations. © The Author(s) 2024.