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Effects of Mineral Trioxide Aggregate and Platelet-Rich Fibrin on Histological Results of Direct Pulp Capping in Dogs Publisher



Ameghani BA1 ; Tavakoli A2 ; Tabatabaei MH3 ; Valizadeh S3, 4
Authors
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Authors Affiliations
  1. 1. Restorative Dentistry Department, Dental School, Birjand University of Medical Sciences, Brjand, Iran
  2. 2. Department of Clinical Sciences, Faculty of Veterinary Medicine, Islamic Azad University, Garmsar Branch, Garmsar, Iran
  3. 3. Restorative Dentistry Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Dental Research Center, Dentistry Research Institute, Tehran University of Medical Science, Tehran, Iran

Source: Giornale Italiano di Endodonzia Published:2021


Abstract

Aim: This study aimed to compare the effects of mineral trioxide aggregate (MTA) and platelet-rich fibrin (PRF) on histological results of direct pulp capping (DPC) in dogs. Methodology: In this animal study, 36 class V cavities were prepared in the incisors of adult healthy mixed-breed dogs. The teeth were then randomly divided into three groups. No material was placed in the control teeth. MTA and PRF were placed on the exposure site in groups 2 and 3, respectively. After two months, the teeth were extracted under general anesthesia and were histological analyzed regarding inflammation, calcified bridge formation and necrosis. Data were analyzed using non-parametric Kruskal-Wallis test. Pairwise comparisons were made using the Mann-Whitney U test. Results: There are no statistically significant differences in terms of pulp inflammation, dentinal bridge formation and necrosis among the treatment groups capping with MTA and PRF. (P Value>0.05), however, PRF and MTA were the same in all parameters, these groups were both significantly superior to the control group. Conclusions: Within the limitations of this study, PRF can be used for DPC as an alternative to MTA. © Societa Italiana di Endodonzia. Production and hosting by Ariesdue. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).