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Expanded Endoscopic Transnasal Approach to the Chordoid Glioma of the Third Ventricle: The First Case Ever Reported Publisher



Zeinalizadeh M1, 2 ; Sadrehosseini SM1, 3 ; Meybodi KT2 ; Sharifabadi AH4
Authors
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Authors Affiliations
  1. 1. Brain and Spinal Cord Injuries Repair Research Center (BASIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Neurological Surgery, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Otolaryngology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Pathology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Korean Neurosurgical Society Published:2016


Abstract

Chordoid glioma of the third ventricle is a rare and challenging tumor to surgery because of its unique anatomical location and its close juxtaposition to the neurovascular structures and hypothalamus. The authors report a case of chordoid glioma of the third ventricle in a 43-year-old woman, who presented with headache and somnolence. The tumor was approached by endoscopic transnasal technique with a favorable result. Histopathologic examination disclosed a neoplastic tissue composed of eosinophilic epithelioid cells, mucinous, periodic acid Schiff-diastase positive, extracellular matrix, and scattered lymphoplasmacytic infiltrates. The best treatment option remains controversial. Customarily, the surgical route to remove chordoid glioma is transcranial; however, the undersurface of the optic chiasm and optic nerves preclude an adequate surgical visualization. In contrast, an expanded endoscopic transnasal approach provides a direct midline corridor to this region without any brain retraction. © 2016 The Korean Neurosurgical Society.