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The Role of Micrornas in Regulating Cytokines and Growth Factors in Coronary Artery Disease: The Ins and Outs Publisher Pubmed



Gorabi AM1 ; Kiaie N1 ; Sathyapalan T2 ; Alrasadi K3 ; Jamialahmadi T4, 5, 6 ; Sahebkar A4, 7, 8, 9
Authors
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Authors Affiliations
  1. 1. Research Center for Advanced Technologies in Cardiovascular Medicine, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Academic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull, Hull, United Kingdom
  3. 3. Medical Research Centre, Sultan Qaboos University, Muscat, Oman
  4. 4. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
  5. 5. Department of Food Science and Technology, Quchan Branch, Islamic Azad University, Quchan, Iran
  6. 6. Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  7. 7. Halal Research Center of IRI, FDA, Tehran, Iran
  8. 8. Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  9. 9. School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Source: Journal of Immunology Research Published:2020


Abstract

Coronary artery diseases (CAD), as a leading cause of mortality around the world, has attracted the researchers' attention for years to find out its underlying mechanisms and causes. Among the various key players in the pathogenesis of CAD cytokines, microRNAs (miRNAs) are crucial. In this study, besides providing a comprehensive overview of the involvement of cytokines, growth factors, and miRNAs in CAD, the interplay between miRNA with cytokine or growth factors during the development of CAD is discussed. © 2020 Armita Mahdavi Gorabi et al.
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