Fabrication of Ketoconazole Nanosuspention, by Pearl Milling Technique and Evaluation, Characterization of Nanocrystals Prepared

Fabrication of Ketoconazole Nanosuspention, by Pearl Milling Technique and Evaluation, Characterization of Nanocrystals Prepared Publisher

Bastami Z¹ ; Panbei M¹ ; Nia ZS¹ ; Hassani M²

Show Affiliations

1. Departments of Medicinal Chemistry, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran
2. Department of Pharmaceutical Biomaterial, Faculty of Pharmacy, Tehran University of Medical sciences, Tehran, Iran

Source: Health Biotechnology and Biopharma Published:2019

Abstract

In the present study, ketoconazole nanosuspentoin were prepared in order to increase solubility by pearl milling technique via solution include Tween 60 and polyvinylpyrrolidone K30 (PVP K30). The Ketoconazole and the resulting ketoconazole nanosuspention were characterized by Fourier-Transform InfraRed spectroscopy (FT-IR) and Differential scanning calorimetry (DSC) analysis. The Atomic force microscopy (AFM) analysis indicated the formation of homogenous and spherical nanosuspention with the final average particle size of around 113.7 nm. Finally the solubility test has shown that ketoconazole nanosuspention solubility has increased. Copyright © 2019, Health Biotechnology and Biopharma. All rights reserved.

Related Docs

1. Formation of Nanosuspensions in Bottom-Up Approach: Theories and Optimization, DARU# Journal of Pharmaceutical Sciences (2019)

2. Size Control in the Nanoprecipitation Process of Stable Iodine (127I) Using Microchannel Reactor—Optimization by Artificial Neural Networks, AAPS PharmSciTech (2015)

3. Design and Optimization of Noscapine Nanosuspensions and Study of Its Cytotoxic Effect, Journal of Biomolecular Structure and Dynamics (2019)

Experts (# of related papers)

Mohammad Ali Faramarzi (1)

Alireza Vatanara (1)

Style	Citing Format
MLA	Bastami Z, et al.. "Fabrication of Ketoconazole Nanosuspention, by Pearl Milling Technique and Evaluation, Characterization of Nanocrystals Prepared." Health Biotechnology and Biopharma, vol. 3, no. 3, 2019, pp. 79-89.
APA	Bastami Z, Panbei M, Nia ZS, Hassani M (2019). Fabrication of Ketoconazole Nanosuspention, by Pearl Milling Technique and Evaluation, Characterization of Nanocrystals Prepared. Health Biotechnology and Biopharma, 3(3), 79-89.
Chicago	Bastami Z, Panbei M, Nia ZS, Hassani M. "Fabrication of Ketoconazole Nanosuspention, by Pearl Milling Technique and Evaluation, Characterization of Nanocrystals Prepared." Health Biotechnology and Biopharma 3, no. 3 (2019): 79-89.
Harvard	Bastami Z et al. (2019) 'Fabrication of Ketoconazole Nanosuspention, by Pearl Milling Technique and Evaluation, Characterization of Nanocrystals Prepared', Health Biotechnology and Biopharma, 3(3), pp. 79-89.
Vancouver	Bastami Z, Panbei M, Nia ZS, Hassani M. Fabrication of Ketoconazole Nanosuspention, by Pearl Milling Technique and Evaluation, Characterization of Nanocrystals Prepared. Health Biotechnology and Biopharma. 2019;3(3):79-89.
BibTex	@article{ author = {Bastami Z and Panbei M and Nia ZS and Hassani M}, title = {Fabrication of Ketoconazole Nanosuspention, by Pearl Milling Technique and Evaluation, Characterization of Nanocrystals Prepared}, journal = {Health Biotechnology and Biopharma}, volume = {3}, number = {3}, pages = {79-89}, year = {2019} }
RIS	TY - JOUR AU - Bastami Z AU - Panbei M AU - Nia ZS AU - Hassani M TI - Fabrication of Ketoconazole Nanosuspention, by Pearl Milling Technique and Evaluation, Characterization of Nanocrystals Prepared JO - Health Biotechnology and Biopharma VL - 3 IS - 3 SP - 79 EP - 89 PY - 2019 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract