Ocular Flare-Up in Patients With Systemic Lupus Erythematosus Following Discontinuation of Hydroxychloroquine

Ocular Flare-Up in Patients With Systemic Lupus Erythematosus Following Discontinuation of Hydroxychloroquine Publisher Pubmed

Ebrahimiadib N¹ ; Riaziesfahani H¹ ; Heidari M¹ ; Mahmoudi A¹

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1. Retina Service, Farabi Eye Hospital, Ophthalmology Department, Tehran University of Medical Sciences, Tehran, Iran

Source: Lupus Published:2020

Abstract

In this report, we describe two patients with systemic lupus erythematosus (SLE) who manifested with posterior segment flare-up approximately three months after cessation of hydroxychloroquine (HCQ). They were stable systemically with no history of hypertension or nephropathy at the time of referral. Our first patient presented with bilateral retinal vein occlusion, while evidence of choroidal involvement such as vascular leakage and wedge-shaped filling delay was present in indocyanine green angiography of both patients. HCQ is well known to have a role in the treatment of SLE for its immunomodulatory and antithrombotic effects. Although reports of systemic flare-up of SLE following HCQ cessation exist in the literature, this is the first report of ocular flare-up in such settings. © The Author(s) 2020.

Style	Citing Format
MLA	Ebrahimiadib N, et al.. "Ocular Flare-Up in Patients With Systemic Lupus Erythematosus Following Discontinuation of Hydroxychloroquine." Lupus, vol. 29, no. 8, 2020, pp. 987-992.
APA	Ebrahimiadib N, Riaziesfahani H, Heidari M, Mahmoudi A (2020). Ocular Flare-Up in Patients With Systemic Lupus Erythematosus Following Discontinuation of Hydroxychloroquine. Lupus, 29(8), 987-992.
Chicago	Ebrahimiadib N, Riaziesfahani H, Heidari M, Mahmoudi A. "Ocular Flare-Up in Patients With Systemic Lupus Erythematosus Following Discontinuation of Hydroxychloroquine." Lupus 29, no. 8 (2020): 987-992.
Harvard	Ebrahimiadib N et al. (2020) 'Ocular Flare-Up in Patients With Systemic Lupus Erythematosus Following Discontinuation of Hydroxychloroquine', Lupus, 29(8), pp. 987-992.
Vancouver	Ebrahimiadib N, Riaziesfahani H, Heidari M, Mahmoudi A. Ocular Flare-Up in Patients With Systemic Lupus Erythematosus Following Discontinuation of Hydroxychloroquine. Lupus. 2020;29(8):987-992.
BibTex	@article{ author = {Ebrahimiadib N and Riaziesfahani H and Heidari M and Mahmoudi A}, title = {Ocular Flare-Up in Patients With Systemic Lupus Erythematosus Following Discontinuation of Hydroxychloroquine}, journal = {Lupus}, volume = {29}, number = {8}, pages = {987-992}, year = {2020} }
RIS	TY - JOUR AU - Ebrahimiadib N AU - Riaziesfahani H AU - Heidari M AU - Mahmoudi A TI - Ocular Flare-Up in Patients With Systemic Lupus Erythematosus Following Discontinuation of Hydroxychloroquine JO - Lupus VL - 29 IS - 8 SP - 987 EP - 992 PY - 2020 ER -

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Abstract