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A Large Dataset of White Blood Cells Containing Cell Locations and Types, Along With Segmented Nuclei and Cytoplasm Publisher Pubmed



Kouzehkanan ZM1, 2 ; Saghari S2, 3 ; Tavakoli S2, 4 ; Rostami P2, 5 ; Abaszadeh M1 ; Mirzadeh F2, 6 ; Satlsar ES2, 7 ; Gheidishahran M8 ; Gorgi F9 ; Mohammadi S10 ; Hosseini R1
Authors
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Authors Affiliations
  1. 1. School of ECE, College of Engineering, University of Tehran, Tehran, Iran
  2. 2. Nimaad Health Equipment Development Company, Tehran, Iran
  3. 3. Graduated Bachelor of Laboratory of Sciences, Paramedical Faculty of Guilan, University of Medical of Sciences, Gilan, Langarud, Iran
  4. 4. Faculty of Electrical Engineering, K. N. Toosi University of Technology, Tehran, Iran
  5. 5. School of Mechanical Engineering, Sharif University of Technology, Tehran, Iran
  6. 6. School of Medicine, Tarbiat Modares University, Tehran, Iran
  7. 7. Flow Cytometry Department, Takhte Tavous Patobiology Lab, Tehran, Iran
  8. 8. Department of Hematology and Blood Transfusion, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran
  9. 9. Bachelor of Laboratory of Sciences, Faculty of Paramedical, Mashhad University of Medical Sciences, Mashhad, Iran
  10. 10. Hematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Scientific Reports Published:2022


Abstract

Accurate and early detection of anomalies in peripheral white blood cells plays a crucial role in the evaluation of well-being in individuals and the diagnosis and prognosis of hematologic diseases. For example, some blood disorders and immune system-related diseases are diagnosed by the differential count of white blood cells, which is one of the common laboratory tests. Data is one of the most important ingredients in the development and testing of many commercial and successful automatic or semi-automatic systems. To this end, this study introduces a free access dataset of normal peripheral white blood cells called Raabin-WBC containing about 40,000 images of white blood cells and color spots. For ensuring the validity of the data, a significant number of cells were labeled by two experts. Also, the ground truths of the nuclei and cytoplasm are extracted for 1145 selected cells. To provide the necessary diversity, various smears have been imaged, and two different cameras and two different microscopes were used. We did some preliminary deep learning experiments on Raabin-WBC to demonstrate how the generalization power of machine learning methods, especially deep neural networks, can be affected by the mentioned diversity. Raabin-WBC as a public data in the field of health can be used for the model development and testing in different machine learning tasks including classification, detection, segmentation, and localization. © 2022, The Author(s).