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Value of Canadian C-Spine Rule Versus the Nexus Criteria in Ruling Out Clinically Important Cervical Spine Injuries: Derivation of Modified Canadian C-Spine Rule Publisher Pubmed



Ghelichkhani P1 ; Shahsavarinia K2 ; Gharekhani A3 ; Taghizadieh A4 ; Baratloo A5, 6 ; Fattah FHR7 ; Abbasi N8 ; Gubari MIM9 ; Faridaalee G9 ; Dinpanah H10 ; Yekaninejad MS11 ; Esmaeili A12 ; Jones ME13 ; Askarianamiri S14 Show All Authors
Authors
  1. Ghelichkhani P1
  2. Shahsavarinia K2
  3. Gharekhani A3
  4. Taghizadieh A4
  5. Baratloo A5, 6
  6. Fattah FHR7
  7. Abbasi N8
  8. Gubari MIM9
  9. Faridaalee G9
  10. Dinpanah H10
  11. Yekaninejad MS11
  12. Esmaeili A12
  13. Jones ME13
  14. Askarianamiri S14
  15. Yousefifard M14
  16. Hosseini M11, 15
Show Affiliations
Authors Affiliations
  1. 1. Department of Intensive Care Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  3. 3. Department of Clinical Pharmacy (Pharmacotherapy), Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Tuberculosis and Lung Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  5. 5. Pre-Hospital and Hospital Research Center, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Emergency Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Community Medicine, College of Medicine, University of Sulaimani, Sulaimani, Iraq
  8. 8. Department of Emergency Medicine, Maragheh University of Medical Sciences, Maragheh, Iran
  9. 9. Community Health Department, Technical College of Health, Sulaimani Polytechnic University, Sulaimani, Iraq
  10. 10. Emergency Department, 9-Day Hospital, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran
  11. 11. Department of Epidemiology and Biostatistics School of Public Health, Tehran University of Medical Sciences, Poursina Ave, Tehran, Iran
  12. 12. Department of Emergency Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  13. 13. Division of Genetics and Epidemiology, The Institute of Cancer Research, London, United Kingdom
  14. 14. Physiology Research Center, School of Medicine, Iran University of Medical Sciences, Hemmat Highway, Tehran, Iran
  15. 15. Pediatric Chronic Kidney Disease Research Center, University of Medical Sciences, Tehran, Iran

Source: Radiologia Medica Published:2021


Abstract

Purpose: Although, Canadian C-spine rule and the National Emergency X-Radiography Utilization Study (NEXUS) criteria in ruling out clinically important cervical spine injuries have been validated using large prospective studies, no consensus exist as to which rule should be endorsed. Therefore, the aim of the present study was to compare the accuracy of the Canadian C-spine and NEXUS criteria in ruling out clinically important cervical spine injuries in trauma patients. Finally, we introduced the modified Canadian C-spine rule. Methods: A prospective diagnostic accuracy study was conducted on trauma patients referred to four emergency departments of Iran in 2018. Emergency physicians evaluated the patients based on the Canadian C-spine rule and NEXUS criteria in two groups of low risk and high risk for clinically important cervical spine injury. Afterward, all patients underwent cervical imaging. In addition, modified Canadian C-spine rule was derived by removing dangerous mechanism and simple rear-end motor vehicle collision from the model. Results: Data from 673 patients were included. The area under the curve of the NEXUS criteria, Canadian C-spine, and modified Canadian C-spine rule were 0.76 [95% confidence interval (CI) 0.71–0.81)], 0.78 (95% CI 0.74–0.83), and 0.79 (95% CI 0.74–0.83), respectively. The sensitivities of NEXUS criteria, Canadian C-spine, and modified Canadian C-spine rule were 93.4%, 100.0% and 100.0%, respectively. Conclusions: The modified Canadian C-spine rule has fewer variables than the original Canadian C-spine rule and is entirely based on physical examination, which seems easier to use in emergency departments. © 2020, Italian Society of Medical Radiology.