Successful Treatment of a Morbihan's Disease Patient After a Therapeutic Challenge: A Case Report and Comprehensive Literature Review Publisher



Bazargan AS¹ ; Dehnavi AZ² ; Dehghani A¹ ; Hesari KK³ ; Jafari P¹ ; Goodarzi A¹
Source: Journal of General and Family Medicine Published:2024

Abstract

Morbihan's disease is a rare condition characterized by chronic facial edema. While its exact cause is unknown, it is thought to involve local cutaneous vascularization and lymphatic drainage imbalance. Traditional treatment options are often ineffective, and no established efficient treatment exists. We present a case study of a 17-year-old male with Morbihan's syndrome who showed resistance to traditional treatments but responded well to a combination of cromolyn sodium nasal spray and oral montelukast after histopathology revealed hyperplasia of plasma cells and mast cells. This combination has not been used before for Morbihan's syndrome. Our review of the literature also provides insight for clinicians seeking to manage this condition. © 2024 The Authors. Journal of General and Family Medicine published by John Wiley & Sons Australia, Ltd on behalf of Japan Primary Care Association.