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The Effect of Maternal and Infant Factors on Cord Blood Yield Publisher Pubmed



Mousavi SH1 ; Abroun S2 ; Zarrabi M3 ; Ahmadipanah M3
Authors
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Authors Affiliations
  1. 1. Department of Hematology, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Hematology, School of Medical Sciences, Tarbiat Modarres University, Tehran, Iran
  3. 3. Royan Stem Cell Technology Institute, Cord Blood Bank, Tehran, Iran

Source: Pediatric Blood and Cancer Published:2017


Abstract

Umbilical cord blood (CB) can be used as an alternative hematopoietic stem cell source for transplantation in hematological malignancy and blood disorders. The success of transplantation is highly related to the levels of total nucleated cell and CD34+ cell counts. The evaluation of optimal conditions can decrease the rate of graft rejection due to low cell count and increases the quality of CB units (CBUs) in the blood bank and the success rate of engraftment. To this end, we review the maternal and infant parameters affecting the quality and quantity of CBUs. © 2016 Wiley Periodicals, Inc.
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