Extensive Biatrial Thrombus in Transit Across a Patent Foramen Ovale: Prompt Diagnosis and Management

Extensive Biatrial Thrombus in Transit Across a Patent Foramen Ovale: Prompt Diagnosis and Management—A Case Report Publisher Pubmed

Mehrpooya M¹ ; Faramarzpour M¹ ; Rahmanian M² ; Fallahtafti P³ ; Eftekhari MR¹

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1. Department of Cardiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Cardiac Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
3. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: BMC Cardiovascular Disorders Published:2025

Abstract

Background: Thrombus in transit (TIT), a rare and life-threatening condition, poses risks of pulmonary and paradoxical embolism which needs prompt diagnosis. Our case report highlights the significance of utilizing advanced imaging techniques for accurate and timely diagnosis of TIT and the potential life-saving role of surgical thrombectomy. Case summary: This case report discusses a rare instance of biatrial thrombus associated with venous thromboembolism (VTE) and patent foramen ovale (PFO). A 66-year-old female with multiple comorbidities presented with dyspnea and fatigue. Imaging revealed large thrombi in both atria, extending via PFO. Concurrent acute deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE) were identified. Emergency cardiac surgery successfully removed the thrombi, emphasizing the diagnostic and management challenges associated with biatrial thrombus and PFO. Conclusion: Point-of-care ultrasound (POCUS) plays a critical role in rapidly identifying TIT across a PFO. The time-sensitive and multidisciplinary medical management of TIT is crucial, requiring individualized strategies. Clinical trial number: Not applicable. Key clinical message: POCUS can be very helpful in providing a more appropriate image and more accurate diagnosis in patients with pulmonary embolism related to thrombus in transit (TIT) which is one of the most life-threatening medical conditions. © The Author(s) 2025.

Style	Citing Format
MLA	Mehrpooya M, et al.. "Extensive Biatrial Thrombus in Transit Across a Patent Foramen Ovale: Prompt Diagnosis and Management—A Case Report." BMC Cardiovascular Disorders, vol. 25, no. 1, 2025, pp. -.
APA	Mehrpooya M, Faramarzpour M, Rahmanian M, Fallahtafti P, Eftekhari MR (2025). Extensive Biatrial Thrombus in Transit Across a Patent Foramen Ovale: Prompt Diagnosis and Management—A Case Report. BMC Cardiovascular Disorders, 25(1), -.
Chicago	Mehrpooya M, Faramarzpour M, Rahmanian M, Fallahtafti P, Eftekhari MR. "Extensive Biatrial Thrombus in Transit Across a Patent Foramen Ovale: Prompt Diagnosis and Management—A Case Report." BMC Cardiovascular Disorders 25, no. 1 (2025): -.
Harvard	Mehrpooya M et al. (2025) 'Extensive Biatrial Thrombus in Transit Across a Patent Foramen Ovale: Prompt Diagnosis and Management—A Case Report', BMC Cardiovascular Disorders, 25(1), pp. -.
Vancouver	Mehrpooya M, Faramarzpour M, Rahmanian M, Fallahtafti P, Eftekhari MR. Extensive Biatrial Thrombus in Transit Across a Patent Foramen Ovale: Prompt Diagnosis and Management—A Case Report. BMC Cardiovascular Disorders. 2025;25(1):-.
BibTex	@article{ author = {Mehrpooya M and Faramarzpour M and Rahmanian M and Fallahtafti P and Eftekhari MR}, title = {Extensive Biatrial Thrombus in Transit Across a Patent Foramen Ovale: Prompt Diagnosis and Management—A Case Report}, journal = {BMC Cardiovascular Disorders}, volume = {25}, number = {1}, pages = {-}, year = {2025} }
RIS	TY - JOUR AU - Mehrpooya M AU - Faramarzpour M AU - Rahmanian M AU - Fallahtafti P AU - Eftekhari MR TI - Extensive Biatrial Thrombus in Transit Across a Patent Foramen Ovale: Prompt Diagnosis and Management—A Case Report JO - BMC Cardiovascular Disorders VL - 25 IS - 1 SP - EP - PY - 2025 ER -

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