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Assessment of the Efficacy of Handmade Vacuum-Assisted Sponge Drain for Treatment of Anastomotic Leakage After Low Anterior Rectal Resection Publisher Pubmed



Keshvari A1, 2 ; Mollamohammadi L1, 2 ; Keramati MR1, 2 ; Behboudi B1, 2 ; Fazeli MS1, 2 ; Kazemeini A1, 2 ; Naseri A1, 2 ; Shahmohammadi E3 ; Foroutani L3 ; Ayati A3 ; Tayebi A3 ; Sajjadian Z4 ; Hadizadeh A3 ; Ahmaditafti SM1, 2
Authors
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Authors Affiliations
  1. 1. Colorectal Research Center, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Division of Colorectal Surgery, Department of Surgery, Tehran University of Medical Sciences, Tehran, 1419733141, Iran
  3. 3. Research Center for Advanced Technologies in Cardiovascular Medicine, Cardiovascular Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran

Source: Updates in Surgery Published:2023


Abstract

Anastomotic leakage is one of the major complications of colorectal surgery, which might lead to reoperation, increased hospital stays, further intervention and mortality. Vacuum-assisted closure by devices such as Endo-SPONGE® produced by (B-Braun Medical B.V.) is currently being used to treat leakage and fistula. In this study, we aimed to assess the handmade vacuum-assisted sponge drain for anastomotic leakage following low anterior resection. This prospective study included 22 patients who had undergone sponge drain placement to treat anastomotic leakage. All patients had anastomotic leaks or defects after left anterior rectal resection (LAR) without ileostomy. They were treated with neo-adjuvant chemotherapy before the surgery and then subjected to rigid recto-sigmoidoscopy for 30 days following the operation. Any sign of leakage, such as perianal and pelvic pain, was immediately identified and followed up with a CT scan and another recto-sigmoidoscopy. Twenty-two patients were enrolled in this study, 12 men (54.5%) and 10 women (47.4%). All patients had received neo-adjuvant chemotherapy with an average follow-up of 22.30 ± 3.81. 75% of patients (15 cases) were successfully treated, and 17 patients (85%) underwent successful ostomy closure. Treatment failed in 5 patients (25%), including three men and two women. This study shows that handmade vacuum-assisted sponge drain is a cost-effective method of anastomotic leakage management with efficacy similar to that of Endo-SPONGE®. Graphical abstract: [Figure not available: see fulltext.] © 2023, Italian Society of Surgery (SIC).