Demographic Patterns and Histopathological Trends of Scalp Tumors in a Dermatology Clinic Publisher



A Shalviri ALIREZA ; Ah Ehsani Ala H ; N Namakizadeh Esfahani NAVID ; S Heidari SAMA ; A Ehsani AMIRHOUSHANG ; Sh Mirmasoumi Seyedeh HANIEH ; A Rahimnia AMIRHOSSEIN
Source: Iranian Journal of Dermatology Published:2025

Abstract

Background: The scalp is a unique anatomical region characterized by a stratified structure and a high incidence of both benign and malignant tumor growth. In this study, we aimed to retrospectively evaluate the demographic and histopathological diagnostic factors associated with scalp tumors in patients. Methods: This cross-sectional study involved 267 patients with scalp tumors who were referred to the dermatology clinic at Razi Hospital in Tehran, Iran. Data were collected from the patients’ medical records. Statistical analysis was conducted using SPSS version 26. Results: This study evaluated a cohort of 267 patients with scalp tumors, comprising 198 men and 69 women, with a mean age of 68.66 ± 9.78 years. Statistical analysis revealed a significant correlation between tumor type and sex (P = 0.000), with male patients exhibiting higher frequencies across all tumor types. The most commonly diagnosed tumor was basal cell carcinoma (BCC), which primarily presented as pigmented and nodular lesions at baseline. BCC was predominantly located in the temporal and frontal regions, while other prevalent tumors, such as actinic keratosis and squamous cell carcinoma, were primarily found on the vertex (P = 0.028). Conclusion: Demographic variables are significant predictors of the presentation and types of scalp tumors in patients, as demonstrated by the results of this study. Clinicians should be aware of the correlation between specific tumor types and their anatomical locations, as this knowledge may assist them in accurately diagnosing and treating scalp tumors. © 2025 Elsevier B.V., All rights reserved.