Topical Use of Matricaria Recutita L (Chamomile) Oil in the Treatment of Monosymptomatic Enuresis in Children: A Double-Blind Randomized Controlled Trial Publisher Pubmed



Sharifi H¹ ; Minaie MB¹ ; Qasemzadeh MJ² ; Ataei N³ ; Gharehbeglou M² ; Heydari M⁴
Source: Journal of Evidence-Based Complementary and Alternative Medicine Published:2017

Abstract

Aim.: To evaluate the efficacy of topical use of Matricaria recutita L oil in the treatment of enuresis in children. Methods.: Eighty patients diagnosed as monosymptomatic nocturnal or daytime enuresis were allocated to receive Matricaria recutita L (chamomile) oil or placebo topically for 6 weeks in a double-blind randomized placebo-controlled trial with a parallel design. Patients were evaluated prior to and following 8 weeks of the intervention in terms of frequency of enuresis and any observed adverse events. Results.: The mean frequency of enuresis at the first, second, and third 2 weeks was lower in the intervention group compared with the placebo group, and the differences were statistically significant (P <.001, P =.03, and P <.001, respectively). There was no report of any adverse event in the study groups. Conclusion.: The findings of this study showed that the topical use of (chamomile) oil can decrease the frequency of nocturia in children with monosymptomatic nocturnal or daytime enuresis. © 2015, © The Author(s) 2015.