Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Efficacy of Different Adhesive Systems in Bonding Direct Resin Composite Restorations: A Systematic Review and Meta-Analysis Publisher



Saini RS1 ; Vyas R1 ; Vaddamanu SK1 ; Quadri SA1 ; Mosaddad SA2, 3 ; Heboyan A2, 4, 5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Allied Dental Health Sciences, COAMS, King Khalid University, Abha, Saudi Arabia
  2. 2. Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India
  3. 3. Department of Prosthodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
  4. 4. Department of Prosthodontics, Faculty of Stomatology, Yerevan State Medical University after Mkhitar Heratsi, Yerevan, Armenia
  5. 5. Department of Prosthodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran

Source: Evidence-Based Dentistry Published:2025


Abstract

Objective: This study aimed to identify and evaluate scholarly research on the efficacy, durability, and long-term stability of various adhesive systems used for bonding direct resin composite restorations and to identify factors influencing bonding performance, such as adhesive composition, application protocol, substrate type, and etching technique. Materials and methods: An all-inclusive electronic database search for peer-reviewed scholarly journal articles was conducted using PubMed, ScienceDirect, Google Scholar, Dimensions, and the Cochrane Library for research articles investigating the effectiveness of different adhesive systems in direct resin composite restorations, excluding reviews, meta-analyses, opinion pieces, and case reports. The risk of bias was assessed using the Cochrane tool (Robvis 2.0). Data were extracted and thematically analyzed, and quantitative data were statistically analyzed using Review Manager software. Dichotomous data were evaluated using the Mantel-Haenszel method, applying a random effects model and 95% confidence interval. Results: The database search yielded 1632 potential articles, of which 14 were included in this study. Several adhesive systems exhibit excellent tensile bond strength. In addition, the type of resin composite, adhesive system, and artificial aging significantly influenced the bonding performance of resin composite restorations. However, the failure rates were low in the different adhesive systems, showing comparable results between the two-step etch-and-rinse and one-step self-etch adhesive systems (p = 0.71). The results showed an overall trend of high bonding effectiveness with a low incidence of adverse events, such as postoperative sensitivity, adhesive failure, and fractures. Conclusion: The study results emphasize the importance of selecting appropriate adhesive systems based on clinical case requirements, restoration characteristics, and patient factors to enhance bonding efficacy, durability, and long-term stability. © The Author(s), under exclusive licence to British Dental Association 2025.
Related Docs
1. Quantum Mechanical Analysis of Yttrium-Stabilized Zirconia and Alumina: Implications for Mechanical Performance of Esthetic Crowns, European Journal of Medical Research (2024)
2. Dental Biomaterials Redefined: Molecular Docking and Dynamics-Driven Dental Resin Composite Optimization, BMC Oral Health (2024)
3. Investigating the Role of Temperature and Moisture on the Degradation of 3D-Printed Polymethyl Methacrylate Dental Materials Through Molecular Dynamics Simulations, Scientific Reports (2024)
4. In Silico Assessment of Biocompatibility and Toxicity: Molecular Docking and Dynamics Simulation of Pmma-Based Dental Materials for Interim Prosthetic Restorations, Journal of Materials Science: Materials in Medicine (2024)
5. Effect of Different Surface Treatments on the Long-Term Repair Bond Strength of Aged Methacrylate-Based Resin Composite Restorations: A Systematic Review and Network Meta-Analysis, BioMed Research International (2022)