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Neuromuscular Manifestations of Lead Poisoning in Opium and Herbal Users in Iran Publisher Pubmed



Okhovat AA1 ; Ansari B2 ; Basiri K2 ; Fatehi F1, 3
Authors
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Authors Affiliations
  1. 1. Faculty of Medicine, Tehran University of Medical Sciences, Shariati Hospital, North Kargar Street, Tehran, Iran
  2. 2. Department of Neurology, Isfahan University of Medical Sciences, Alzahra Hospital, Isfahan, Iran
  3. 3. CNRS (UMR 7339), centre de resonance magnetique biologique et medicale, faculte de medecine, Aix Marseille University, 27, boulevard J. Moulin, Marseille, 13005, France

Source: Revue Neurologique Published:2020


Abstract

Opium sale is prohibited in Iran, and sellers mix it with lead to increase the weight. Herein, we describe neuromuscular findings in nine patients who developed lead poisoning due to opium/drug consumption. The mean age of patients was 53 ± 3.5 years and their mean blood lead level was 122.6 ± 20.8 μg/dL. Most of the patients had an acute/subacute course presenting as axonal or demyelinating sensorimotor polyneuropathy, motor neuron disease, and multiple mononeuropathies with favorable response to the chelation therapy. Lead poisoning should be considered in patients with a history of opium use and neuromuscular symptoms. © 2020 Elsevier Masson SAS
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3. Lead Poisoning Among Asymptomatic Individuals With a Long-Term History of Opiate Use in Golestan Cohort Study, International Journal of Drug Policy (2022)
4. Blood Lead Levels and Multiple Sclerosis: A Case-Control Study, Multiple Sclerosis and Related Disorders (2019)
5. Opium - an Unusual Cause of Lead Poisoning: A Case Series, Govaresh (2021)
6. Lead Poisoning Outbreak Among Opium Users in the Islamic Republic of Iran, 2016-2017; [Vague D’Intoxications Au Plomb Chez Les Consommateurs D’Opium En Republique Islamique D’Iran, 2016-2017]; [Brote De Intoxicacion Con Plomo Entre Consumidores De Opio En La Republica Islamica Del Iran, De 2016 a 2017], Bulletin of the World Health Organization (2018)
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