The Role of High Dose Corticosteroid (Methylperednisolone Pulse Therapy) in Treatment of Multi-Organ Involvement After Bacterial Pneumonia and Pleural Empyema; “Case Series”

The Role of High Dose Corticosteroid (Methylperednisolone Pulse Therapy) in Treatment of Multi-Organ Involvement After Bacterial Pneumonia and Pleural Empyema; “Case Series” Publisher Pubmed

Mirlohi SH¹ ; Tajfirooz S² ; Rouhi M²

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1. Pediatric Respiratory and Sleep Medicine Research Center, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
2. Children’s Medical Center, Pediatric Center of Excellence, Tehran, Iran

Source: BMC Infectious Diseases Published:2025

Abstract

Parapneumonic effusions and empyema usually occur after bacterial pneumonia. Inflammation plays an essential role in the occurrence of pneumonia and can lead to an autoinflammatory condition. In this study, we will present three cases including multi-organ involvement following pleural empyema that have been treated with pulse corticosteroid therapy. Apparently, pleural empyema can lead to multi-organ involvement due to underlying inflammatory processes. This condition is usually associated with symptoms and changes in laboratory parameters that manifest after empyema treatment or reappear after temporary recovery. Hence, managing this condition by pulse corticosteroid therapy can result in positive outcomes. © The Author(s) 2025.

2. Is a New Post-Infectious Inflammatory Phenomenon Emerging? Increasing Evidence of a New Multiple Organ Involvement Syndrome in Children, Iranian Journal of Pediatrics (2023)

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Mohamad Reza Abdosalehi (1)

Masoud Mohammad Pour (1)

Style	Citing Format
MLA	Mirlohi SH, Tajfirooz S, Rouhi M. "The Role of High Dose Corticosteroid (Methylperednisolone Pulse Therapy) in Treatment of Multi-Organ Involvement After Bacterial Pneumonia and Pleural Empyema; “Case Series”." BMC Infectious Diseases, vol. 25, no. 1, 2025, pp. -.
APA	Mirlohi SH, Tajfirooz S, Rouhi M (2025). The Role of High Dose Corticosteroid (Methylperednisolone Pulse Therapy) in Treatment of Multi-Organ Involvement After Bacterial Pneumonia and Pleural Empyema; “Case Series”. BMC Infectious Diseases, 25(1), -.
Chicago	Mirlohi SH, Tajfirooz S, Rouhi M. "The Role of High Dose Corticosteroid (Methylperednisolone Pulse Therapy) in Treatment of Multi-Organ Involvement After Bacterial Pneumonia and Pleural Empyema; “Case Series”." BMC Infectious Diseases 25, no. 1 (2025): -.
Harvard	Mirlohi SH, Tajfirooz S, Rouhi M (2025) 'The Role of High Dose Corticosteroid (Methylperednisolone Pulse Therapy) in Treatment of Multi-Organ Involvement After Bacterial Pneumonia and Pleural Empyema; “Case Series”', BMC Infectious Diseases, 25(1), pp. -.
Vancouver	Mirlohi SH, Tajfirooz S, Rouhi M. The Role of High Dose Corticosteroid (Methylperednisolone Pulse Therapy) in Treatment of Multi-Organ Involvement After Bacterial Pneumonia and Pleural Empyema; “Case Series”. BMC Infectious Diseases. 2025;25(1):-.
BibTex	@article{ author = {Mirlohi SH and Tajfirooz S and Rouhi M}, title = {The Role of High Dose Corticosteroid (Methylperednisolone Pulse Therapy) in Treatment of Multi-Organ Involvement After Bacterial Pneumonia and Pleural Empyema; “Case Series”}, journal = {BMC Infectious Diseases}, volume = {25}, number = {1}, pages = {-}, year = {2025} }
RIS	TY - JOUR AU - Mirlohi SH AU - Tajfirooz S AU - Rouhi M TI - The Role of High Dose Corticosteroid (Methylperednisolone Pulse Therapy) in Treatment of Multi-Organ Involvement After Bacterial Pneumonia and Pleural Empyema; “Case Series” JO - BMC Infectious Diseases VL - 25 IS - 1 SP - EP - PY - 2025 ER -

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