Primary Cutaneous Lymphoma-Associated Pseudoepitheliomatous Hyperplasia Masquerading As Squamous Cell Carcinoma in a Young Adult

Primary Cutaneous Lymphoma-Associated Pseudoepitheliomatous Hyperplasia Masquerading As Squamous Cell Carcinoma in a Young Adult Pubmed

Ansari M¹ ; Ardalan FA² ; Najafi M³ ; Goodarzi A¹ ; Ghanadan A^{2, 4}

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1. Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Surgery, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Acta Medica Iranica Published:2015

Abstract

Primary cutaneous anaplastic large cell lymphoma is a T-cell malignancy with atypical CD30 positive lymphocytes. Pseudoepitheliomatous hyperplasia is an uncommon finding in primary cutaneous anaplastic large cell lymphoma, and may mimic squamous cell carcinoma as pseudomalignancy. Careful attention of a pathologist to correct diagnosis of pseudoepitheliomatous hyperplasia and its underlying causes will help physicians to avoid inappropriate management. Here, we present a 22-year-old man referred to our hospital with a solitary nodule persistent on his forearm which was diagnosed as squamous cell carcinoma in the first biopsy. The lesion recurred after two months and histopathologic and immunohistochemistry examination revealed anaplastic large cell lymphoma with florid pseudoepitheliomatous hyperplasia which masquerading as well-differentiated squamous cell carcinoma. Diagnosis of pseudoepitheliomatous hyperplasia must guide the pathologist to search for underlying causes, such as primary cutaneous lymphoma. Pseudoepitheliomatous hyperplasia may mimic squamous cell carcinoma and this can result in inappropriate diagnosis and management. © 2015 Tehran University of Medical Sciences. All rights reserved.

Style	Citing Format
MLA	Ansari M, et al.. "Primary Cutaneous Lymphoma-Associated Pseudoepitheliomatous Hyperplasia Masquerading As Squamous Cell Carcinoma in a Young Adult." Acta Medica Iranica, vol. 53, no. 12, 2015, pp. 785-788.
APA	Ansari M, Ardalan FA, Najafi M, Goodarzi A, Ghanadan A (2015). Primary Cutaneous Lymphoma-Associated Pseudoepitheliomatous Hyperplasia Masquerading As Squamous Cell Carcinoma in a Young Adult. Acta Medica Iranica, 53(12), 785-788.
Chicago	Ansari M, Ardalan FA, Najafi M, Goodarzi A, Ghanadan A. "Primary Cutaneous Lymphoma-Associated Pseudoepitheliomatous Hyperplasia Masquerading As Squamous Cell Carcinoma in a Young Adult." Acta Medica Iranica 53, no. 12 (2015): 785-788.
Harvard	Ansari M et al. (2015) 'Primary Cutaneous Lymphoma-Associated Pseudoepitheliomatous Hyperplasia Masquerading As Squamous Cell Carcinoma in a Young Adult', Acta Medica Iranica, 53(12), pp. 785-788.
Vancouver	Ansari M, Ardalan FA, Najafi M, Goodarzi A, Ghanadan A. Primary Cutaneous Lymphoma-Associated Pseudoepitheliomatous Hyperplasia Masquerading As Squamous Cell Carcinoma in a Young Adult. Acta Medica Iranica. 2015;53(12):785-788.
BibTex	@article{ author = {Ansari M and Ardalan FA and Najafi M and Goodarzi A and Ghanadan A}, title = {Primary Cutaneous Lymphoma-Associated Pseudoepitheliomatous Hyperplasia Masquerading As Squamous Cell Carcinoma in a Young Adult}, journal = {Acta Medica Iranica}, volume = {53}, number = {12}, pages = {785-788}, year = {2015} }
RIS	TY - JOUR AU - Ansari M AU - Ardalan FA AU - Najafi M AU - Goodarzi A AU - Ghanadan A TI - Primary Cutaneous Lymphoma-Associated Pseudoepitheliomatous Hyperplasia Masquerading As Squamous Cell Carcinoma in a Young Adult JO - Acta Medica Iranica VL - 53 IS - 12 SP - 785 EP - 788 PY - 2015 ER -

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