A Review: Fda-Approved Fluorine-Containing Small Molecules From 2015 to 2022

A Review: Fda-Approved Fluorine-Containing Small Molecules From 2015 to 2022 Publisher Pubmed

Sheikhi N¹ ; Bahraminejad M¹ ; Saeedi M^{2, 3} ; Mirfazli SS¹

Show Affiliations

1. Department of Medicinal Chemistry, School of Pharmacy, Iran University of Medical Sciences, Tehran, Iran
2. Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
3. Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: European Journal of Medicinal Chemistry Published:2023

Abstract

Fluorine-containing small molecules have occupied a special position in drug discovery research. The successful clinical use of fluorinated corticosteroids in the 1950s and fluoroquinolones in the 1980s led to an ever-increasing number of approved fluorinated compounds over the last 50 years. They have shown various biological properties such as antitumor, antimicrobial, and anti-inflammatory activities. Fluoro-pharmaceuticals have been considered a strong and practical tool in the rational drug design approach due to their benefits from potency and ADME (absorption, distribution, metabolism, and excretion) points of view. Herein, approved fluorinated drugs from 2015 to 2022 were reviewed. © 2023 Elsevier Masson SAS

2. Recent Advances in Non-Small Cell Lung Cancer Targeted Therapy; an Update Review, Cancer Cell International (2023)

3. Mode and Site of Action of Therapies Targeting Cgrp Signaling, Journal of Headache and Pain (2023)

Experts (# of related papers)

Azarakhsh Mokri (1)

Style	Citing Format
MLA	Sheikhi N, et al.. "A Review: Fda-Approved Fluorine-Containing Small Molecules From 2015 to 2022." European Journal of Medicinal Chemistry, vol. 260, no. , 2023, pp. -.
APA	Sheikhi N, Bahraminejad M, Saeedi M, Mirfazli SS (2023). A Review: Fda-Approved Fluorine-Containing Small Molecules From 2015 to 2022. European Journal of Medicinal Chemistry, 260(), -.
Chicago	Sheikhi N, Bahraminejad M, Saeedi M, Mirfazli SS. "A Review: Fda-Approved Fluorine-Containing Small Molecules From 2015 to 2022." European Journal of Medicinal Chemistry 260, no. (2023): -.
Harvard	Sheikhi N et al. (2023) 'A Review: Fda-Approved Fluorine-Containing Small Molecules From 2015 to 2022', European Journal of Medicinal Chemistry, 260(), pp. -.
Vancouver	Sheikhi N, Bahraminejad M, Saeedi M, Mirfazli SS. A Review: Fda-Approved Fluorine-Containing Small Molecules From 2015 to 2022. European Journal of Medicinal Chemistry. 2023;260():-.
BibTex	@article{ author = {Sheikhi N and Bahraminejad M and Saeedi M and Mirfazli SS}, title = {A Review: Fda-Approved Fluorine-Containing Small Molecules From 2015 to 2022}, journal = {European Journal of Medicinal Chemistry}, volume = {260}, number = {}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Sheikhi N AU - Bahraminejad M AU - Saeedi M AU - Mirfazli SS TI - A Review: Fda-Approved Fluorine-Containing Small Molecules From 2015 to 2022 JO - European Journal of Medicinal Chemistry VL - 260 IS - SP - EP - PY - 2023 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract