Antibacterial Activity of Amphiphilic Polymers Publisher



Gholipourmalekabadi M^{1, 2} ; Pande NS³ ; Rathore BS⁴ ; Pal Singh Chauhan N⁵
Source: Biocidal Polymers Published:2019

Abstract

Increasing prevalence of multi-drug resistant bacteria has remained as a main challenge in medical care units. Several studies are being conducted to develop an effective and novel antibacterial agent with broad-spectrum antibacterial activity against resistant bacteria and non-cytotoxicity for human cells. Among them, amphiphilic polymers have many interesting antibacterial, biological and mechanical properties such as target-based activity against microorganisms, biodegradability, biocompatibility, good mechanical strength and cell adhesion, which make them a promising candidate for biomedical applications. Amphiphilic polymers possess both hydrophilic (water-loving, polar) and lipophilic (fat-loving) or hydrophobic (water-hating) properties. In this chapter, different amphiphilic polymers, their synthesis procedures, antibacterial and biological properties, as well as possible applications as antibacterial agents in biomedicine are discussed in details. © 2020 Walter de Gruyter GmbH, Berlin/Boston.