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Actinomycotic Osteomyelitis of the Maxilla in a Patient on Phenytoin Publisher



Aghahosseini F1, 2 ; Hoseini EG3 ; Mahdavi N4
Authors
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Authors Affiliations
  1. 1. Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Oral and Maxillofacial Medicine, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Oral & Maxillofacial Medicine, School of Dentistry, Kashan University of Medical Sciences, Kashan, Iran
  4. 4. Department Oral and Maxillofacial Pathology, School of Dentistry, Tehran University of Medical Science, Tehran, Iran

Source: Frontiers in Dentistry Published:2022


Abstract

Actinomycosis is caused by Actinomyces species and is relatively rare in humans. Because of the special collateral blood flow, osteomyelitis is less common in the maxilla than the mandible. Although there are few case reports for jaw osteomyelitis, actinomycotic osteomyelitis associated with phenytoin therapy has not been reported before. The data show that antiepileptic drugs induce suppression of the immune system. This report presents a rare case of a 58-year-old man on phenytoin with actinomycotic osteomyelitis, and reviews the relevant literature. © 2022 The Authors. Published by Tehran University of Medical Sciences.