An Efficient One-Pot Synthesis of 3-Aryl-5-(Dialkoxymethyl)-1,2,4-Oxadiazoles Under Solvent-Free Conditions

An Efficient One-Pot Synthesis of 3-Aryl-5-(Dialkoxymethyl)-1,2,4-Oxadiazoles Under Solvent-Free Conditions Publisher

Adib M¹ ; Saeedi S¹ ; Soheilizad M¹ ; Bayanati M¹ ; Tajbakhsh M² ; Amanlou M³

Show Affiliations

1. School of Chemistry, College of Science, University of Tehran, P.O. Box 14155-6455, Tehran, Iran
2. Department of Organic Chemistry, Faculty of Chemistry, Mazandaran University, Babolsar, Iran
3. Pharmaceutical Sciences Research Center, Department of Medicinal Chemistry, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Chemical Research Published:2016

Abstract

An efficient and simple synthesis of 3-aryl-5-(dialkoxymethyl)-1,2,4-oxadiazoles is described. The in situ prepared amidoximes from the reaction between nitriles and hydroxylamine are condensed with alkyl 2,2-dialkoxyacetates under solvent-free conditions to produce the title compounds in excellent yields. © 2016, Science Reviews 2000 Ltd. All rights reserved.

Style	Citing Format
MLA	Adib M, et al.. "An Efficient One-Pot Synthesis of 3-Aryl-5-(Dialkoxymethyl)-1,2,4-Oxadiazoles Under Solvent-Free Conditions." Journal of Chemical Research, vol. 40, no. 5, 2016, pp. 314-317.
APA	Adib M, Saeedi S, Soheilizad M, Bayanati M, Tajbakhsh M, Amanlou M (2016). An Efficient One-Pot Synthesis of 3-Aryl-5-(Dialkoxymethyl)-1,2,4-Oxadiazoles Under Solvent-Free Conditions. Journal of Chemical Research, 40(5), 314-317.
Chicago	Adib M, Saeedi S, Soheilizad M, Bayanati M, Tajbakhsh M, Amanlou M. "An Efficient One-Pot Synthesis of 3-Aryl-5-(Dialkoxymethyl)-1,2,4-Oxadiazoles Under Solvent-Free Conditions." Journal of Chemical Research 40, no. 5 (2016): 314-317.
Harvard	Adib M et al. (2016) 'An Efficient One-Pot Synthesis of 3-Aryl-5-(Dialkoxymethyl)-1,2,4-Oxadiazoles Under Solvent-Free Conditions', Journal of Chemical Research, 40(5), pp. 314-317.
Vancouver	Adib M, Saeedi S, Soheilizad M, Bayanati M, Tajbakhsh M, Amanlou M. An Efficient One-Pot Synthesis of 3-Aryl-5-(Dialkoxymethyl)-1,2,4-Oxadiazoles Under Solvent-Free Conditions. Journal of Chemical Research. 2016;40(5):314-317.
BibTex	@article{ author = {Adib M and Saeedi S and Soheilizad M and Bayanati M and Tajbakhsh M and Amanlou M}, title = {An Efficient One-Pot Synthesis of 3-Aryl-5-(Dialkoxymethyl)-1,2,4-Oxadiazoles Under Solvent-Free Conditions}, journal = {Journal of Chemical Research}, volume = {40}, number = {5}, pages = {314-317}, year = {2016} }
RIS	TY - JOUR AU - Adib M AU - Saeedi S AU - Soheilizad M AU - Bayanati M AU - Tajbakhsh M AU - Amanlou M TI - An Efficient One-Pot Synthesis of 3-Aryl-5-(Dialkoxymethyl)-1,2,4-Oxadiazoles Under Solvent-Free Conditions JO - Journal of Chemical Research VL - 40 IS - 5 SP - 314 EP - 317 PY - 2016 ER -

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