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Idiopathic Granulomatous Mastitis: Looking for the Most Effective Therapy With the Least Side Effects According to the Severity of the Disease in 374 Patients in Iran Publisher Pubmed



Kaviani A1, 2, 3 ; Vasigh M1 ; Omranipour R1, 2 ; Mahmoudzadeh H1, 2 ; Elahi A4 ; Farivar L5 ; Zand S6
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Authors Affiliations
  1. 1. Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Breast Disease Research Centre, TUMS, Tehran, Iran
  3. 3. University of Montreal, Montreal, Canada
  4. 4. Alborz University of Medical Sciences, Karaj, Iran
  5. 5. University of Miami School of Medicine, Miami, FL, United States
  6. 6. Kaviani Breast Disease Institute, Tehran, Iran

Source: Breast Journal Published:2019


Abstract

The goal of this study is to compare the response rate and the recurrence rate of available therapeutic modalities in the treatment of Idiopathic Granulomatous Mastitis (IGM). 374 patients with pathologically confirmed IGM, were included. They were subdivided into three levels of severity. Close observation had the best response rate with the lowest recurrence rate in mild to moderate cases. Severe cases were mostly treated by prednisolone or underwent surgery. The outcome of prednisolone use in severe cases was comparable to NSAIDs. Overall 9% were resistant to treatment and surgical intervention is still an option among them. © 2019 Wiley Periodicals, Inc.
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