Tehran University of Medical Sciences

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Post-Traumatic Stress Disorder or Emergence Phenomena? a Case of Psychomotor Agitation After Procedural Sedation and Analgesia Publisher Pubmed



Jalali A1 ; Akbari H2 ; Bahreini M3
Authors
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Authors Affiliations
  1. 1. Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Imam-Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Prehospital and Hospital Emergency Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Drug Metabolism and Personalized Therapy Published:2019


Abstract

Psychomotor agitation can be problematic in an overcrowded emergency department (ED) during uncontrolled procedural sedation. Although emergence phenomena have been studied, various presentations may exist. During procedural sedation, a 58-year-old man was sedated with a dissociative dose of ketamine in conjunction with propofol. His shoulder dislocation was reduced successfully but eventually, an exaggerated agitation occurred resembling a post-traumatic stress disorder (PTSD) flashback of past war scenes He was controlled by physical and chemical restraint with an intramuscular injection of 0.1 mg/kg midazolam. After resolution of sedation in rather stable psychiatric conditions, he left the ED with his relatives insisting for discharge against medical advice. A PTSD flashback may occur from ketamine sedation in patients with a past history of military experience and can be a manifestation of psychologic adverse effects of ketamine. © 2019 Walter de Gruyter GmbH, Berlin/Boston.