Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Association of Limb-Girdle Muscular Dystrophy With Multiple Sclerosis: A Case Report Publisher



Arzani M1 ; Rezaei H2 ; Moghadasi AN1, 3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Neurology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Urology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Sina MS Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Caspian Journal of Internal Medicine Published:2018


Abstract

Background: The association of limb-girdle muscular dystrophy (LGMD) with other neurological disorders is uncommon. Case presentation: We report a 25-year-old female with LGMD who suffered from slowly progressive proximal muscular weakness and atrophy since she was 12 years of age. The patient recently presented with acute loss of left side visual acuity. After evaluation, findings were suggestive of multiple sclerosis. Conclusions: This is the first report of LGMD in association with MS. The simultaneous occurrence of MS with myopathies may be incidental but there may be a genetic susceptibility for both diseases. This comorbidity may influence the treatment of MS.
Related Docs
View other Related Docs
1. The Epidemiologic Trend of Multiple Sclerosis in Razavi Khorasan Province, Iran in Fifteen-Year Period, Multiple Sclerosis and Related Disorders (2025)
2. Cervical and Ocular Vestibular Evoked Myogenic Potentials in Multiple Sclerosis Participants, Medical Journal of the Islamic Republic of Iran (2015)
3. Altered Topological Properties of Brain Networks in the Early Ms Patients Revealed by Cognitive Task-Related Fmri and Graph Theory, Biomedical Signal Processing and Control (2018)
4. Association of Two Polymorphisms in Msh2 and Xrcc1 Genes With Multiple Sclerosis in Iranian Population, Physiology and Pharmacology (2016)
5. Trail Gene Expression Analysis in Multiple Sclerosis Patients, Human Antibodies (2016)
6. Utility of Myelin Basic Protein As an Early Prognostic Biomarker in Multiple Sclerosis, Iranian Red Crescent Medical Journal (2017)
7. Age and Sex Adjusted Prevalence and Annual Incidence of Multiple Sclerosis in East-Azerbaijan, Iran, Multiple Sclerosis and Related Disorders (2021)
8. Clinical Characteristics and Disability Progression of Early-And Late-Onset Multiple Sclerosis Compared to Adult-Onset Multiple Sclerosis, Journal of Clinical Medicine (2020)
Experts (# of related papers)
View all Related Experts
Mohammad Ali Sahraian (6)
Sharareh Eskandarieh (1)
Other Related Docs
9. Smoking and Worsening Disability in Multiple Sclerosis: A Meta-Analysis, Acta Neurologica Scandinavica (2018)
10. Multiple Sclerosis Epidemiology in Middle East and North Africa: A Systematic Review and Meta-Analysis, Neuroepidemiology (2015)
11. Multiple Sclerosis and Ulcerative Colitis: A Systematic Review and Meta-Analysis, Multiple Sclerosis Journal - Experimental# Translational and Clinical (2023)
12. Multiple Sclerosis Epidemiology in East Asia, South East Asia and South Asia: A Systematic Review, Neuroepidemiology (2016)
13. Early Predictors of Conversion to Secondary Progressive Multiple Sclerosis, Multiple Sclerosis and Related Disorders (2021)