Rehabilitation of Mandibulectomy With Patient-Specific Instrument: A Case Report Publisher

Summary: Can CAD/CAM technology revolutionize recovery after extensive mandibular resection? A case study suggests it enables rapid rehabilitation, with full function restored in just 24 hours. #OralSurgery #CADCAM

Parhiz A ; Karimpour M ; Farahmand F ; Damercheli S ; Amirzade Iranaq MH
Source: Journal of Craniomaxillofacial Research Published:2025

Abstract

We present a treatment option for extensive mandibular resection using CAD/CAM technology. This option allows for the patient’s immediate and complete rehabilitation and has advantages over autografts. A 73-year-old female patient was diagnosed with Central Giant Cell Granuloma (CGCG). The proposed treatment plan involved an angle-to-angle resection of the mandible along with free flap surgery using an autologous iliac graft; however, the patient declined this option. As a final treatment plan, the possibility of utilizing a customized titanium prosthesis as a patient-specific implant (PSI) was considered. The patient was discharged in good general condition, and remarkably, full function was recovered within 24 hours. Additionally, the patient was able to speak and eat after just 5 hours, a testament to the swift recovery this treatment option offers. The primary benefits of this method are immediate results and swift, accurate surgical procedures, which provide reassurance of its efficiency. © 2025 Tehran University of Medical Sciences.