Effective Combination Therapy With High Concentration of Minoxidil and Carboxygas in Resistant Androgenetic Alopecia: Report of Nine Cases Publisher Pubmed



Nilforooshzadeh MA^{1, 2} ; Lotfi E^{1, 2} ; Heidarikharaji M^{1, 2} ; Zolghadr S^{1, 2} ; Mansouri P¹ Show Affiliations
Source: Journal of Cosmetic Dermatology Published:2020

Abstract

Background: Androgenetic alopecia (AGA) is widely characterized as the main reason of hair loss which most of the time it has been reported in adults regarding dermatological consultation. Also, it is broadly believed that the progressive miniaturization of hair follicles could be usually different at the age of onset. Aims: Over the last decade, detecting and understanding newer genetic basis in AGA lead to provide better therapeutic approaches. We have highlighted on an evidence-based method to treat AGA whose incidence is increasing significantly in our country. Patients/Methods: In this study, 9 adults with AGA including 5 women and 4 men, age range of 25-55 years, were treated with a combination of minoxidil (20%) by micro-needling and carboxytherapy mediated by needling. All cases had a normal physical development. Hair numbers (density) and diameter were calculated using trichograms before and after treatment. Hair growth was assessed by the pull test as well. Results: Our results showed that combination of high concentration of minoxidil and carboxygas extremely can increase the level of hair growth. Conclusion: Our treatment effects on the terminal follicles using needling make sticky follicles become progressively smaller as a result of mechanical forces. © 2020 Wiley Periodicals, Inc.