Efficacy of Polyunsaturated Fatty Acids (Pufa) in the Treatment of Attention Deficit Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Efficacy of Polyunsaturated Fatty Acids (Pufa) in the Treatment of Attention Deficit Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Publisher Pubmed

Assareh M^{1, 6} ; Davari Ashtiani R⁶ ; Khademi M² ; Jazayeri S³ ; Rai A⁴ ; Nikoo M⁵

Show Affiliations

1. Alborz University of Medical Sciences, Karaj, Iran
2. Shahid Beheshti University of Medical Sciences, Tehran, Iran
3. Tehran University of Medical Sciences, Iran
4. Kermanshah University of Medical Sciences, Iran
5. Farzan Clinical Research Institute, Tehran, Iran
6. Department of Psychiatry, Imam Hossein Hospital and Behavioral Sciences Research Center Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Journal of Attention Disorders Published:2017

Abstract

Objective: We aimed to investigate the efficacy of polyunsaturated fatty acids (PUFAs) as an adjuvant treatment in patients with ADHD receiving methylphenidate as well as its side effects. Method: This randomized clinical trial was conducted on 40 ADHD patients aged between 6 and 12 years. Both treatment and placebo groups received methylphenidate. Treatment arm also received omega-6 once daily. The Parent ADHD Rating Scale was used to evaluate disease improvement. Results: The Parent ADHD Rating Scale scores of the two groups were similar at baseline. Although total score and scores of three categories decreased significantly in both groups, total score and scores of inattention, hyperactivity, and impulsivity were not significantly different between the groups. Conclusion: The results did not support the efficacy of PUFA in the treatment of ADHD, and adding PUFAs to the therapeutic regimen of ADHD is not recommended at the moment. © 2012, © The Author(s) 2012.

Experts (# of related papers)

Roja Rahimi (1)

Shahin Akhondzadeh Basti (1)

Style	Citing Format
MLA	Assareh M, et al.. "Efficacy of Polyunsaturated Fatty Acids (Pufa) in the Treatment of Attention Deficit Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial." Journal of Attention Disorders, vol. 21, no. 1, 2017, pp. 78-85.
APA	Assareh M, Davari Ashtiani R, Khademi M, Jazayeri S, Rai A, Nikoo M (2017). Efficacy of Polyunsaturated Fatty Acids (Pufa) in the Treatment of Attention Deficit Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Journal of Attention Disorders, 21(1), 78-85.
Chicago	Assareh M, Davari Ashtiani R, Khademi M, Jazayeri S, Rai A, Nikoo M. "Efficacy of Polyunsaturated Fatty Acids (Pufa) in the Treatment of Attention Deficit Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial." Journal of Attention Disorders 21, no. 1 (2017): 78-85.
Harvard	Assareh M et al. (2017) 'Efficacy of Polyunsaturated Fatty Acids (Pufa) in the Treatment of Attention Deficit Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial', Journal of Attention Disorders, 21(1), pp. 78-85.
Vancouver	Assareh M, Davari Ashtiani R, Khademi M, Jazayeri S, Rai A, Nikoo M. Efficacy of Polyunsaturated Fatty Acids (Pufa) in the Treatment of Attention Deficit Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Journal of Attention Disorders. 2017;21(1):78-85.
BibTex	@article{ author = {Assareh M and Davari Ashtiani R and Khademi M and Jazayeri S and Rai A and Nikoo M}, title = {Efficacy of Polyunsaturated Fatty Acids (Pufa) in the Treatment of Attention Deficit Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial}, journal = {Journal of Attention Disorders}, volume = {21}, number = {1}, pages = {78-85}, year = {2017} }
RIS	TY - JOUR AU - Assareh M AU - Davari Ashtiani R AU - Khademi M AU - Jazayeri S AU - Rai A AU - Nikoo M TI - Efficacy of Polyunsaturated Fatty Acids (Pufa) in the Treatment of Attention Deficit Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial JO - Journal of Attention Disorders VL - 21 IS - 1 SP - 78 EP - 85 PY - 2017 ER -

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