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Efficacy of Nd:Yag Laser-Assisted Periodontal Therapy for the Management of Periodontitis: A Double-Blind Split-Mouth Randomized Controlled Clinical Trial Publisher Pubmed



Dortaj D1, 8 ; Bassir SH2 ; Hakimiha N1, 3 ; Hong H4 ; Aslroosta H5 ; Fekrazad R6, 9 ; Moslemi N7
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Authors Affiliations
  1. 1. Laser Research Center of Dentistry, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Periodontology, School of Dental Medicine, Stony Brook University, Stony Brook, NY, United States
  3. 3. Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Department of Family, Population and Preventive Medicine, Stony Brook University, Stony Brook, NY, United States
  5. 5. Department of Periodontology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Radiation Sciences Research Center, Laser Research Center in Medical Sciences, AJA University of Medical Sciences, School of Dentistry, Tehran, Iran
  7. 7. Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Operative Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  9. 9. International Network for Photo Medicine and Photo Dynamic Therapy (INPMPDT), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Journal of Periodontology Published:2022


Abstract

Background: This study aimed to explore the efficacy of Nd:YAG laser-assisted periodontal therapy for management of patients with stage II-IV periodontitis. Methods: Patients who presented with residual periodontal pockets were enrolled. After non-surgical periodontal therapy (NSPT), test sites received Nd:YAG laser (first entrance to pocket: 3 W, 100 μs, 20 Hz; second entrance: 4 W, 600 μs, 20 Hz) and control sites received placebo (laser off). Periodontal probing depth (PPD), clinical attachment level (CAL), gingival recession (GR), bleeding on probing (BOP), and plaque index (PI) were recorded at baseline and 1, 2, 3, 4 and 6-month visits. Results: Twenty patients completed the 6-month period. Significant reductions in PPD, CAL, BOP, and PI values and a significant increase in GR at all follow-up visits compared to the baseline (all P < 0.001) were revealed in both groups. Test sites showed significantly greater improvement in PPD (P = 0.0002) and greater increase in GR (P < 0.0001) compared to the control sites at 6-month visit. There was no difference between two groups regarding CAL gain through the study period (P = 0.23). Conclusion: NSPT+Nd:YAG laser with the current protocol results in greater PPD reduction compared to NSPT alone. However, this reduction is likely because of greater GR rather than attachment gain. Therefore, the adjunction of Nd:YAG laser (with the current setting) to the NSPT for the treatment of residual periodontal pockets did not ameliorate the clinical outcomes (ClinicalTrials.gov ID: NCT03365167). © 2021 American Academy of Periodontology.
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