Intragastric Botulinum Toxin Injection and Botulism: An Alarm for Clinicians

Intragastric Botulinum Toxin Injection and Botulism: An Alarm for Clinicians Publisher

Mojtahedzadeh M¹ ; Najmeddin F¹ ; Pourheidar E² ; Najafi A³ ; Bahman R⁴ ; Yousefimazhin E¹ ; Karballaeimirzahosseini H¹ ; Hassanpour R¹

Show Affiliations

1. Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Intensive Care Unit, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
3. Department of Anesthesiology and Critical Care, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
4. Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Case Reports in Critical Care Published:2024

Abstract

Clostridium botulinum produces the most potent bacterial toxin, botulinum toxin A (BTXA), which has various therapeutic and cosmetic indications. Intragastric BTXA injection is a new obesity treatment method that was argued to be safe due to the inactivation of BTXA through the liver or metabolization within the gastric wall. However, a 36-year-old woman was admitted to the intensive care unit (ICU) due to developing botulism as a result of an intragastric injection of BTXA. The diplopia, headaches, ptosis, decreased muscle force, and respiratory distress two days after injection were her first chief complaints, and also, she experienced significant dysphagia, hoarse voice, thick tongue, constipation, hyposmia, and hypogeusia after two weeks. This case report highlights the necessity for physicians to have sufficient information about this method and consider possible life-threatening adverse effects including botulism. © 2024 Mojtaba Mojtahedzadeh et al.

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Style	Citing Format
MLA	Mojtahedzadeh M, et al.. "Intragastric Botulinum Toxin Injection and Botulism: An Alarm for Clinicians." Case Reports in Critical Care, vol. 2024, no. , 2024, pp. -.
APA	Mojtahedzadeh M, Najmeddin F, Pourheidar E, Najafi A, Bahman R, Yousefimazhin E, Karballaeimirzahosseini H, Hassanpour R (2024). Intragastric Botulinum Toxin Injection and Botulism: An Alarm for Clinicians. Case Reports in Critical Care, 2024(), -.
Chicago	Mojtahedzadeh M, Najmeddin F, Pourheidar E, Najafi A, Bahman R, Yousefimazhin E, Karballaeimirzahosseini H, Hassanpour R. "Intragastric Botulinum Toxin Injection and Botulism: An Alarm for Clinicians." Case Reports in Critical Care 2024, no. (2024): -.
Harvard	Mojtahedzadeh M et al. (2024) 'Intragastric Botulinum Toxin Injection and Botulism: An Alarm for Clinicians', Case Reports in Critical Care, 2024(), pp. -.
Vancouver	Mojtahedzadeh M, Najmeddin F, Pourheidar E, Najafi A, Bahman R, Yousefimazhin E, et al.. Intragastric Botulinum Toxin Injection and Botulism: An Alarm for Clinicians. Case Reports in Critical Care. 2024;2024():-.
BibTex	@article{ author = {Mojtahedzadeh M and Najmeddin F and Pourheidar E and Najafi A and Bahman R and Yousefimazhin E and Karballaeimirzahosseini H and Hassanpour R}, title = {Intragastric Botulinum Toxin Injection and Botulism: An Alarm for Clinicians}, journal = {Case Reports in Critical Care}, volume = {2024}, number = {}, pages = {-}, year = {2024} }
RIS	TY - JOUR AU - Mojtahedzadeh M AU - Najmeddin F AU - Pourheidar E AU - Najafi A AU - Bahman R AU - Yousefimazhin E AU - Karballaeimirzahosseini H AU - Hassanpour R TI - Intragastric Botulinum Toxin Injection and Botulism: An Alarm for Clinicians JO - Case Reports in Critical Care VL - 2024 IS - SP - EP - PY - 2024 ER -

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