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A Simple One-Pot Synthesis of 2,4-Diaryl- 9H-Pyrido[2,3-B]Indoles Under Solvent-Free Conditions Publisher



Khoshneviszadeh M1 ; Yahagh A2 ; Soheilizad M2 ; Mahdavi M3
Authors
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Authors Affiliations
  1. 1. Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  2. 2. School of Chemistry, College of Science, University of Tehran, Tehran, Iran
  3. 3. Drug Design and Development Research Center, Tehran University of Medical Sciences, P.O. Box 1417614411, Tehran, Iran

Source: Heterocyclic Communications Published:2017


Abstract

A novel, simple, one-pot synthesis of 2,4-diaryl-9H-pyrido[2,3-b]indoles is described. Heating a mixture of chalcone, oxindole and ammonium acetate in the presence of potassium tert-butoxide under solvent-free conditions afforded the title compounds in good to excellent yields. © 2017 Walter de Gruyter GmbH, Berlin/Boston 2017.