Lymph Node Evaluation in Colorectal Cancer Patients in Iran Publisher



Kalirad A¹ ; Babaei J² ; Niknejad SN³ Show Affiliations
Source: Biomedical and Pharmacology Journal Published:2016

Abstract

Introduction: Colorectal cancer is the third and fourth major cause of cancer prevalence and also mortality among males and females, respectively in Iran. The number of Lymph Nodes which are remain associated after surgery, are one of the pre-notice aspects which influence on patients. This study aimed to investigate the rate of adequacy of lymph node in patients with colorectal cancer in Tehran, Iran. This study was a retrospective investigation and the studied population was the patients who had been hospitalized with colorectal cancer in Imam Khomeini Hospital, Tehran, Iran. Data on patient and tumor variables were collected from charts of 1095 patients aged, diagnosed at our hospital in 2005-2014. 877 colorectal cancer patients were evaluated for involvement of lymph nodes during study. 495 subjects (56.4%) were male with the mean age of 51.34±12.23 and 382 patients (43.6%) were female with average age of 50.51±13.41. The mean number of evaluated lymph nodes in total period of the study was 8. The minimum number of involved lymph nodes in the patients was 0 and 91 cases showed such situation and maximum number of involved lymph nodes in patients was 25 that included 1.03% of the patients. with regards to importance of definition of involved lymph nodes in prognosis and chance of survival in the patients and also suggestion of national cancer institute to define at least 12 lymph nodes for determination of disease stage, it is advised that definition of involved lymph nodes conduct with higher accuracy.