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Strongyloides Stercoralis Hyperinfection in an Unconscious Diabetic Patient With Dermatomyositis Publisher Pubmed



Sharifdini M1 ; Hesari A2 ; Mahdavi SA3 ; Alipour A4, 5 ; Kia EB4, 5
Authors
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Authors Affiliations
  1. 1. Department of Medical Parasitology and Mycology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
  2. 2. Emergency Department of Emam Reza Hospital, Qom Medical Center, Social Security Organization, Qom, Iran
  3. 3. Department of Medical Parasitology and Mycology, Amol Faculty of Paramedics, Mazandaran University of Medical Sciences, Sari, Iran
  4. 4. Center for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Iran
  5. 5. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, P. O. Box: 14155-6446, Tehran, Iran

Source: Indian Journal of Pathology and Microbiology Published:2018


Abstract

A case of Strongyloides stercoralis hyperinfection in a patient with dermatomyositis and diabetes mellitus is herein reported. The case was a 60-year-old female admitted due to watery diarrhea and unconsciousness. She had a 10-year history of chronic immunosuppressive therapy including methotrexate and prednisolone for dermatomyositis. Stool parasitological examination revealed numerous rhabditiform larvae of threadworm 'S. stercoralis.' Larva in stool sample was characterized by sequencing of mitochondrial DNA. After treatment with ivermectin, the patient recovered without evidence of S. stercoralis in follow-up stool samples. In endemic areas, stool examination for detection of S. stercoralis should be performed on a regular basis for all patients receiving immunosuppressive therapy, as early detection and treatment are necessary to minimize complications of severe strongyloidiasis. © 2018 Indian Journal of Pathology and Microbiology. All rights reserved.